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Table 1 Clinical data of study participants

From: Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults

Indices   Probiotic group (PG) Control group (CG) PG vs CG
(n = 71) (n = 66) P-values
Sex (female/male)   58/13 58/8 0.443
Age (y) Mean (SD) 49.6 (6.5) 49.9 (6.1) 0.821
  Median (percentile 25–75 %) 50 (45–54) 49 (46–54)
Body mass index (kg/m2) Mean (SD) 25.9 (3.8) 26.7 (4.1) 0.277
  Median (percentile 25–75 %) 26.6 (23–29) 26.2 (24–29)
Systolic blood pressure (mmHg) Mean (SD) 117.2 (13.8) 119.6 (11.2) 0.271
  Median (percentile 25–75 %) 116 (106–129) 119 (113–126)
Diastolic blood pressure (mmHg) Mean (SD) 77.7 (8.9) 81.1 (8.4) 0.022
  Median (percentile 25–75 %) 77.5 (72–83) 81.8 (75–85)
Fasting glucose (mmol/l) Mean (SD) 4.8 (0.5) 4.6 (0.6) 0.218
  Median (percentile 25–75 %) 4.8 (4.4–5.1) 4.6 (4.4–4.9)
HbA1c (%) Mean (SD) 5.8 (0.3) 5.7 (0.3) 0.467
  Median (percentile 25–75 %) 5.8 (5.6–6.0) 5.7 (5.5–6.0)
Total cholesterol (mmol/l) Mean (SD) 5.9 (0 · 7) 6.0 (0.8) 0.584
  Median (percentile 25–75 %) 5.8 (5.4–6.2) 5.9 (5.3–6.5)
LDL cholesterol (mmol/l) Mean (SD) 3.8 (0.7) 3.7 (0.8) 0.441
  Median (percentile 25–75 %) 3.8 (3.3–4.3) 3.7 (3.2–4.1)
HDL cholesterol (mmol/l) Mean (SD) 1.7 (0.5) 1.8 (0.5) 0.109
  Median (percentile 25–75 %) 1.5 (1.3–2.1) 1.8 (1.5–2.1)
LDL-C:HDL-C ratio Mean (SD) 2.4 (0.9) 2.2 (0.8) 0.110
  Median (percentile 25–75 %) 2.3 (1.8–3.1) 2.1 (1.7–2.6)
Triglyceride (mmol/l) Mean (SD) 1.2 (0.7) 1.1 (0.5) 0.706
  Median (percentile 25–75 %) 1.0 (0.7–1.5) 0.9 (0.8–1.2)  
  1. Data represent the mean ± standard deviation and median (CI 25 % and 75 %). For continuous variables, the differences between groups were tested with the Student’s t-test, and gender distributions were compared with Fisher’s exact test. The only statistical difference was found in the level of diastolic blood pressure (NORIP, http://www.tandfonline.com/doi/pdf/10.1080/00365510410006324#.Vhpmx27-VCE)