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Table 1 Clinical data of study participants

From: Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults

Indices

 

Probiotic group (PG)

Control group (CG)

PG vs CG

(n = 71)

(n = 66)

P-values

Sex (female/male)

 

58/13

58/8

0.443

Age (y)

Mean (SD)

49.6 (6.5)

49.9 (6.1)

0.821

 

Median (percentile 25–75 %)

50 (45–54)

49 (46–54)

Body mass index (kg/m2)

Mean (SD)

25.9 (3.8)

26.7 (4.1)

0.277

 

Median (percentile 25–75 %)

26.6 (23–29)

26.2 (24–29)

Systolic blood pressure (mmHg)

Mean (SD)

117.2 (13.8)

119.6 (11.2)

0.271

 

Median (percentile 25–75 %)

116 (106–129)

119 (113–126)

Diastolic blood pressure (mmHg)

Mean (SD)

77.7 (8.9)

81.1 (8.4)

0.022

 

Median (percentile 25–75 %)

77.5 (72–83)

81.8 (75–85)

Fasting glucose (mmol/l)

Mean (SD)

4.8 (0.5)

4.6 (0.6)

0.218

 

Median (percentile 25–75 %)

4.8 (4.4–5.1)

4.6 (4.4–4.9)

HbA1c (%)

Mean (SD)

5.8 (0.3)

5.7 (0.3)

0.467

 

Median (percentile 25–75 %)

5.8 (5.6–6.0)

5.7 (5.5–6.0)

Total cholesterol (mmol/l)

Mean (SD)

5.9 (0 · 7)

6.0 (0.8)

0.584

 

Median (percentile 25–75 %)

5.8 (5.4–6.2)

5.9 (5.3–6.5)

LDL cholesterol (mmol/l)

Mean (SD)

3.8 (0.7)

3.7 (0.8)

0.441

 

Median (percentile 25–75 %)

3.8 (3.3–4.3)

3.7 (3.2–4.1)

HDL cholesterol (mmol/l)

Mean (SD)

1.7 (0.5)

1.8 (0.5)

0.109

 

Median (percentile 25–75 %)

1.5 (1.3–2.1)

1.8 (1.5–2.1)

LDL-C:HDL-C ratio

Mean (SD)

2.4 (0.9)

2.2 (0.8)

0.110

 

Median (percentile 25–75 %)

2.3 (1.8–3.1)

2.1 (1.7–2.6)

Triglyceride (mmol/l)

Mean (SD)

1.2 (0.7)

1.1 (0.5)

0.706

 

Median (percentile 25–75 %)

1.0 (0.7–1.5)

0.9 (0.8–1.2)

 
  1. Data represent the mean ± standard deviation and median (CI 25 % and 75 %). For continuous variables, the differences between groups were tested with the Student’s t-test, and gender distributions were compared with Fisher’s exact test. The only statistical difference was found in the level of diastolic blood pressure (NORIP, http://www.tandfonline.com/doi/pdf/10.1080/00365510410006324#.Vhpmx27-VCE)