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Table 1 Demographic and laboratory characteristics of study populationa

From: Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients

 

Hemodialysis

(n = 35)

Control

(n = 17)

P

Age,b y

49 ± 15

45 ± 11

0.25

Race, n (%)

 African American

28 (80)

11 (65)

 

 Caucasian

7 (20)

6 (35)

0.23

Male sex, n (%)

28 (80)

13 (76)

0.77

Primary Disorder of ESRD, n (%)

 Hypertension

14 (40)

  

 Diabetes Mellitus

7 (20)

  

 Glomerulonephritis

7 (20)

  

 RCC Bilateral Nephrectomy

1 (3)

NA

 Polycystic Kidney Disease

1 (3)

  

 Other

5 (14)

  

Dialysis Vintage,c months

34 (17, 120)

 

NA

Body Composition

 BMI,b kg/m2

29 ± 6

28 ± 7

0.34

 Truncal Fat,b %

38 ± 13

33 ± 12

0.09

 Fat Mass,c kg

30 (23, 37)

24 (15, 31)

0.21

 Lean Mass,c kg

52 (49, 61)

59 (47, 66)

0.34

BUN,b mg/dL

45 ± 16

13 ± 3

<0.001

Creatinine,b mg/dL

9.7 ± 2.9

0.9 ± 0.1

<0.001

Albumin,b g/dL

3.9 ± 0.4

4.0 ± 0.2

0.34

hs-CRP,c mg/L

4.0 (1.8, 10.6)

0.9 (0.4, 3.1)

<0.001

Hematocrit,b %

37 ± 5

43 ± 3

<0.001

Fasting Glucose,b mg/dL

98 ± 17

105 ± 23

0.11

Baseline Insulin,c μU/mL

12.6 (10.7, 19.8)

10.4 (5.2, 13.3)

0.05

HbA1c,b %

5.2 ± 0.6

5.3 ± 0.5

0.33

HOMA-IR,c

2.9 (2.2, 4.4)

2.7 (1.1, 3.5)

0.17

  1. a BUN blood urea nitrogen, ESRD end stage renal disease, HbA1c hemoglobin A1c, hs-CRP high-sensitivity C-reactive protein, HOMA-IR homeostatic model assessment of insulin resistance, RCC renal cell carcinoma
  2. bMean ± SD
  3. cMedian (IQR)