Skip to main content

Table 1 Inclusion and exclusion criteria

From: A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study

Inclusion criteria

 • Willing and able to provide informed consent

 • Willing and able to attend 3 clinic visits

 • Willing and able to eat all foods on Prudent or Western diets

 • Age ≥18 years of age

Exclusion criteria (self reported)

 • Alcoholic beverage intake >14 drinks/week

 • Use of food or nutritional supplements that cannot be discontinued

 • Current use of anti-inflammatory medications that cannot be discontinued

 • Current use of anti-hypertensive medications that cannot be discontinued

 • Current use of anti-cholesterol medications that cannot be discontinued

 • Previous diagnosis of cardiovascular disease or cardiovascular event within past year

 • Body-mass-index ≥45 kg/m2

 • High blood pressure (or on anti-hypertensive medications)

 • Abnormal blood lipids (or on lipid-modifying medications)

 • Diabetes mellitus (FPG ≥ 7.0) or impaired fasting glucose (fasting glucose 6.1 to 6.9)

 • Renal insufficiency or disease

 • Hepatitis or Jaundice

 • Liver disease

 • Tuberculosis

 • HIV/AIDS

 • Active malignancy or cancer treatment within past 1 year

 • Inflammatory bowel disease, malabsorptive states

 • Current asthma (use of bronchodilator ≥1 time in past month)

 • Any chronic disease likely to influence adherence to diet or participation in study

 • Current or planned pregnancy during term of study

 • Current use of oral contraceptives or hormone replacement therapy