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Table 6 Effects of Prudent and Western diets on body weight, blood pressure, and lipid risk factors

From: A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study

 

Prudent (n = 45)

Western (n = 37)*

 
 

Week 0a

Week 2a

Changea

Week 0a

Week 2a

Changea

Prudent minus Westernb*

Body weight

72.6 (16.4)

72.0 (16.1)

-0.6 (1.4)‡

69.3 (13.3)

68.9 (13.0)

-0.4 (1.2)†

-0.1 (-0.7 to 0.4)

Body-mass index (kg/m2)

26.1 (5.6)

25.9 (5.4)

-0.1 (1.3)

25.1 (4.6)

25.0 (4.4)

-0.1 (0.4)

-0.02 (-0.44 to 0.40)

Percent body fat

27.9 (9.0)

28.2 (8.5)

-1.3 (3.2)‡

28.6 (11.7)

29.9 (11.3)

0.3 (3.3)

-1.5 (-2.9 to -0.04)

Blood pressure (mmHg)

 Systolic

118 (17)

114 (16)

-4 (11)†

112 (18)

113 (15)

2 (10)

-4 (-8 to 1)

 Diastolic

74 (10)

70 (10)

-5 (9)§

74 (10)

72 (9)

-1 (6)

-3 (-6 to 0.3)

Lipids (mmol/L)

 Total-Cholesterol

4.92 (1.26)

4.73 (1.24)

-0.19 (0.65)†

5.25 (1.05)

5.23 (1.14)

0.03 (0.51)

-0.24 (-0.51 to 0.03)

 Non-HDL-C

3.43 (1.14)

3.29 (1.13)

-0.14 (0.64)

3.81 (0.94)

3.73 (0.99)

-0.03 (0.55)

-0.15 (-0.42 to 0.12)

  1. Data are presented as aMean (SD) or bmean (95 % CI); *Significance of between-treatment difference in parameter was estimated using analysis of covariance, adjusted for age, sex, and baseline values. Significant between-diet differences are denoted by †(P < 0.05), ‡(P < 0.01), or §(P < 0.001)