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Table 6 Effects of Prudent and Western diets on body weight, blood pressure, and lipid risk factors

From: A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study

  Prudent (n = 45) Western (n = 37)*  
  Week 0a Week 2a Changea Week 0a Week 2a Changea Prudent minus Westernb*
Body weight 72.6 (16.4) 72.0 (16.1) -0.6 (1.4) 69.3 (13.3) 68.9 (13.0) -0.4 (1.2) -0.1 (-0.7 to 0.4)
Body-mass index (kg/m2) 26.1 (5.6) 25.9 (5.4) -0.1 (1.3) 25.1 (4.6) 25.0 (4.4) -0.1 (0.4) -0.02 (-0.44 to 0.40)
Percent body fat 27.9 (9.0) 28.2 (8.5) -1.3 (3.2) 28.6 (11.7) 29.9 (11.3) 0.3 (3.3) -1.5 (-2.9 to -0.04)
Blood pressure (mmHg)
 Systolic 118 (17) 114 (16) -4 (11) 112 (18) 113 (15) 2 (10) -4 (-8 to 1)
 Diastolic 74 (10) 70 (10) -5 (9)§ 74 (10) 72 (9) -1 (6) -3 (-6 to 0.3)
Lipids (mmol/L)
 Total-Cholesterol 4.92 (1.26) 4.73 (1.24) -0.19 (0.65) 5.25 (1.05) 5.23 (1.14) 0.03 (0.51) -0.24 (-0.51 to 0.03)
 Non-HDL-C 3.43 (1.14) 3.29 (1.13) -0.14 (0.64) 3.81 (0.94) 3.73 (0.99) -0.03 (0.55) -0.15 (-0.42 to 0.12)
  1. Data are presented as aMean (SD) or bmean (95 % CI); *Significance of between-treatment difference in parameter was estimated using analysis of covariance, adjusted for age, sex, and baseline values. Significant between-diet differences are denoted by (P < 0.05), (P < 0.01), or §(P < 0.001)