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Table 4 Activity of HMG CoA reductase of males and females rats after 28 days administration of Spirulina platensis

From: Hypolipidemic effect and activation of Lecithin Cholesterol Acyl Transferase (LCAT) by aqueous extract of Spirulina platensis during toxicological investigation

Groups

HMG CoA reductase activity (UI/mg protein)

Rats Males

Rats Females

control

0.38 ± 0.001a

13.45 ± 0.002a

250 mg/kg

0.13 ± 0.002b

3.99 ± 0.000b

500 mg/kg

0.06 ± 0.000c

5.07 ± 0.007c

1000 mg/kg

0.02 ± 0.000d

0.50 ± 0.000d

  1. In the same column, the values subscripted with the same letter are not significantly different at p < 0.05