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Table 3 Whole body glucose kinetics during the oral glucose tolerance test over 4-week dietary intervention

From: Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial

  Recommended Protein Intake Elevated Protein Intake p-value
Pre Post Pre Post Time Group T × G
R a Total, mg/kg/min 3.39 ± 0.13 3.25 ± 0.17 3.75 ± 0.18 3.50 ± 0.19 0.045a 0.192 0.533
R a Endo, mg/kg/min 1.20 ± 0.09 1.22 ± 0.11 1.08 ± 0.09 1.15 ± 0.10 0.062 0.501 0.369
R a Exo, mg/kg/min 2.19 ± 0.15 2.02 ± 0.22 2.67 ± 0.25 2.35 ± 0.20 0.027a 0.174 0.442
R d, mg/kg/min 3.25 ± 0.17 3.06 ± 0.19 3.71 ± 0.18 3.42 ± 0.14 0.015a 0.110 0.544
MCR, ml/kg/min 1.67 ± 0.16 1.68 ± 0.24 1.97 ± 0.36 1.83 ± 0.29 0.486 0.558 0.391
  1. Values are expressed as mean ± SEM
  2. R a Total Rate of appearance of total glucose, R a Endo rate of appearance of endogenous glucose, R a Exo rate of appearance of exogenous glucose, R d rate of disappearance of glucose, MCR metabolic clearance rate of glucose (R d normalized to plasma glucose concentration), T × G time-group interaction
  3. aThere were significant effects on time (i.e., post- vs. pre-intervention). However, post hoc t-test analyses revealed no significant changes from pre- to post-intervention (for all, p > 0.235)