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Table 3 Whole body glucose kinetics during the oral glucose tolerance test over 4-week dietary intervention

From: Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial

 

Recommended Protein Intake

Elevated Protein Intake

p-value

Pre

Post

Pre

Post

Time

Group

T × G

R a Total, mg/kg/min

3.39 ± 0.13

3.25 ± 0.17

3.75 ± 0.18

3.50 ± 0.19

0.045a

0.192

0.533

R a Endo, mg/kg/min

1.20 ± 0.09

1.22 ± 0.11

1.08 ± 0.09

1.15 ± 0.10

0.062

0.501

0.369

R a Exo, mg/kg/min

2.19 ± 0.15

2.02 ± 0.22

2.67 ± 0.25

2.35 ± 0.20

0.027a

0.174

0.442

R d, mg/kg/min

3.25 ± 0.17

3.06 ± 0.19

3.71 ± 0.18

3.42 ± 0.14

0.015a

0.110

0.544

MCR, ml/kg/min

1.67 ± 0.16

1.68 ± 0.24

1.97 ± 0.36

1.83 ± 0.29

0.486

0.558

0.391

  1. Values are expressed as mean ± SEM
  2. R a Total Rate of appearance of total glucose, R a Endo rate of appearance of endogenous glucose, R a Exo rate of appearance of exogenous glucose, R d rate of disappearance of glucose, MCR metabolic clearance rate of glucose (R d normalized to plasma glucose concentration), T × G time-group interaction
  3. aThere were significant effects on time (i.e., post- vs. pre-intervention). However, post hoc t-test analyses revealed no significant changes from pre- to post-intervention (for all, p > 0.235)