The effects of 100% wild blueberry (Vaccinium angustifolium) juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes

Table 4 Effect of 100% wild blueberry juice compared with placebo beverage on biomarkers of inflammation, adhesion molecules, oxidative stress and nitric oxide^a

Variable	Wild blueberry juice	Placebo beverage	P
IL-6 (pg/ml)	0.8 ± 0.07	0.9 ± 0.07	0.203
IL-10 (pg/ml)	0.28 ± 0.02	0.28 ± 0.02	0.659
CRP (ng/ml)	2130.4 ± 52.8	2141.2 ± 53.0	0.887
TNF-α (pg/ml)	2.0 ± 0.4	2.1 ± 0.4	0.399
SAA (ng/ml)	10.1 ± 1.1	10.1 ± 1.1	0.771
sICAM (ng/ml)	305.8 ± 9.6	311.5 ± 9.6	0.551
sVCAM (ng/ml)	969.7 ± 255.5	910.3 ± 256.0	0.665
LDL-oxidation(U/L)	44.5 ± 1.7	44.6 ± 1.7	0.259
Total 8-isoprostanes (pg/ml)	80.1 ± 8.0	80.8 ± 8.0	0.935
Nitric oxide (μM)	4.1 ± 0.4	2.9 ± 0.4	0.039

^a n = 19, females; all values are lsmeans ± SE. Analysis of covariance appropriate for a two period, two treatment crossover study with baseline values prior to each period; interleukin-6 (IL-6), interleukin-10 (IL-10), high sensitivity C-reactive protein (CRP), tumor necrosis factoralpha (TNF-α), serum amyloid A (SAA), soluble intercellular adhesion molecule-1 (sICAM), and soluble vascular adhesion molecule-1 (sVCAM)

ISSN: 2055-0928