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Table 2 Coronary heart disease prevalence by beverage intake frequencies among adults, ages 45–59 y – NHANES 2003–2006

From: Intake of high fructose corn syrup sweetened soft drinks, fruit drinks and apple juice is associated with prevalent coronary heart disease, in U.S. adults, ages 45–59 y

  95% Coronary Heart Diseasea
Proportion Confidence % yes p-value3
% Limits
tEFFb (ndSoda, FD, AJ) (n = 1230)
  ≤ 3 times /mo 43.4% 40.3- 46.6% 3.3% 0.044
 1–4 times /wk. 31.2% 28.1- 34.4% 5.1%  
 5 times or more /wk. 25.4% 22.8- 28.3% 7.9%  
Non-diet soft drinks (n = 1230)
  ≤ 3 times /mo 57.8% 54.9- 60.6% 4.1% 0.037
 1–4 times /wk. 20.8% 18.5- 23.3% 3.9%  
 5 times or more /wk. 21.4% 18.8- 24.3% 8.7%  
Diet soda (n = 1153)
  ≤ 3 times /mo 56.3% 51.9- 60.5% 6.1% 0.406
 1–4 times /wk. 15.3% 12.4- 18.7% 3.7%  
 5 times or more /wk. 28.4% 24.4- 32.8% 4.3%  
Diet fruit drinks (n = 881)
  ≤ 3 times /mo 85.7% 81.9- 88.9% 5.3% 0.286
 1–4 times /wk. 07.7% 05.4- 10.9% 1.1%  
 5 times or more /wk. 06.6% 04.7- 09.1% 5.5%  
Orange juice (n = 1230)
  ≤ 3 times /mo 58.7% 54.2- 63.0% 5.9% 0.239
 1–4 times /wk. 26.2% 22.7- 30.0% 3.2%  
 5 times or more /wk. 15.1% 12.7- 18.0% 5.0%  
  1. aCoronary Heart Disease (CHD) is defined as self-reported current or history of doctor diagnosed CHD and/ or angina pectoris [36]. btEFF refers to total excess free fructose beverages intake which includes any combination of high excess free fructose beverages for the NHANES period of 2003–2006 [35, 36]. This includes average daily intake of caffeinated and caffeine free non-diet soft drinks (ndSoda); non-diet fruit drinks (FD); and naturally high excess free fructose apple juice (AJ) [35, 36]. In 2003–2006 [the NHANES study period], high fructose corn syrup was the main sweetener in US soft drinks [31]. 3) Rao Scott Ҳ2 analysis was used to test for significance of differences in coronary heart disease prevalence by beverage intake frequency. A p-value <0.05 was considered significant and is indicated by italics