Fig. 3

Principal coordinates analysis (PCoA) plot of genus-level data based on Bray-Curtis dissimilarity. Samples are colored according to responder status, defined by lower scores of IBS-SSS and/or pain during the low FODMAP rye bread period compared to baseline. The symbols depicting the treatment. Percentage of the total microbiota variation explained by both variables and their p-values were calculated with permutational multivariate ANOVA