| Group | Intervention effect | |||
---|---|---|---|---|---|
Intervention | Control | Mean difference | Cohen’s d | p | |
Hb, g/dL | |||||
 Baseline | 12.6 ± 0.9 (85)b | 12.4 ± 1.0 (85) | – | – | – |
 At 5 months, unadjusted | 12.6 ± 0.9 (85) | 12.3 ± 1.0 (86) | – | – | – |
 At 5 months, adjustedc | 12.5 (12.4, 12.6) (85)d | 12.4 (12.3, 12.5) (85) | 0.1 (− 0.1, 0.3) | 0.17 | 0.30 |
FER, μg/Le | |||||
 Baseline | 40.4 ± 33.8 (84) | 44.9 ± 40.0 (84) | – | – | – |
 At 5 months, unadjusted | 38.0 ± 27.1 (85) | 47.4 ± 39.6 (86) | – | – | – |
 At 5 months, adjustedc | 39.3 (35.5, 43.0) (84) | 45.8 (42.1, 49.6) (84) | −6.6 (−11.9, − 1.3) | − 0.39 | 0.015 |
sTfR, mg/L | |||||
 Baseline | 5.8 ± 2.6 (84) | 6.3 ± 3.3 (84) | – | – | – |
 At 5 months, unadjusted | 5.9 ± 2.6 (85) | 6.2 ± 3.5 (86) | – | – | – |
 At 5 months, adjustedc | 6.1 (5.9, 6.3) (84) | 5.9 (5.7, 6.1) (84) | 0.2 (−0.1, 0.5) | 0.23 | 0.15 |
RBP, μmol/Le | |||||
 Baseline | 1.37 ± 0.26 (84) | 1.49 ± 0.31 (84) | – | – | – |
 At 5 months, unadjusted | 1.42 ± 0.33 (85) | 1.44 ± 0.35 (86) | – | – | – |
 At 5 months, adjustedc | 1.45 (1.39, 1.52) (84) | 1.40 (1.34, 1.47) (84) | 0.05 (−0.04, 0.14) | 0.17 | 0.27 |
Folate, ng/mL | |||||
 Baseline | 8.0 ± 3.1 (78) | 7.8 ± 2.9 (74) | – | – | – |
 At 5 months, unadjusted | 9.6 ± 4.5 (84) | 8.2 ± 3.2 (84) | – | – | – |
 At 5 months, adjustedc | 9.5 (8.8, 10.3) (78) | 8.4 (7.6, 9.2) (73) | 1.1 (−0.02, 2.2) | 0.32 | 0.054 |