Variables | Baseline | Month 3 | Diffrences between group between group at month 3 | NEP (n = 48) Mean ± SD | Month 6 | C (n = 46) Mean ± SD | P value | Differences between group at month 6 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NEP (=51) Mean ± SD | NE (n = 51) Mean ± SD | C (n = 51 Mean ± SD | P value | NEP (n = 51) Mean ± SD | NE (n = 50) Mean ± SD | C (n = 49) Mean ± SD | P value | NE (n = 49) Mean ± SD | ||||||||||
NEP-NE | NEP-C | NE-C | ||||||||||||||||
1 | 2.61 ± 1.26 | 2.12 ± 0.99 | 2.22 ± 0.73 | 0.12 | 4.31 ± 1.33 | 3.20 ± 1.74 | 1.92 ± 1.64 | < 0.01 | 1.09(0.32)** | 2.36(0.32)** | 1.26(0.32)** | 5.15 ± 1.50 | 4.00 ± 1.80 | 2.71 ± 1.06 | 0.01 | 1.14(0.32)** | 2.38(0.32)** | 1.24(0.32)** |
2 | 2.96 ± 1.23 | 2.55 ± 1.46 | 2.78 ± 1.38 | 0.34 | 3.58 ± 2.31 | 2.68 ± 2.17 | 2.27 ± 2.44 | 0.02 | 0.83(0.47) | 1.26(0.48)* | 0.43(0.47) | 3.98 ± 2.08 | 2.88 ± 2.03 | 2.74 ± 2.10 | 0.02 | 1.03(0.43) | 1.21(0.44)* | 0.18(0.43) |
3 | 3.02 ± 0.68 | 2.80 ± 0.66 | 2.80 ± 0.63 | 0.17 | 5.84 ± 1.89 | 3.88 ± 2.45 | 3.63 ± 2.62 | < 0.01 | 1.76(0.46)** | 2.01(0.46)** | 0.26(0.46) | 6.02 ± 1.59 | 4.06 ± 2.12 | 4.06 ± 2.12 | 0.000 | 1.83(0.41)** | 1.92(0.42)** | 0.9(0.41) |
4 | 2.49 ± 0.90 | 2.52 ± 1.13 | 2.51 ± 1.13 | 0.99 | 3.94 ± 1.49 | 2.60 ± 1.51 | 1.77 ± 1.61 | < 0.01 | 1.36(0.32)** | 2.17(0.31)** | 0.81(0.31)* | 3.85 ± 1.46 | 2.61 ± 1.53 | 1.73 ± 1.51 | 0.000 | 1.24(0.31)** | 2.1(0.32)** | 0.87(0.31)* |
5 | 2.68 ± 1.49 | 2.84 ± 1.16 | 2.52 ± 1.29 | 0.53 | 3.50 ± 1.35 | 2.46 ± 1.50 | 1.43 ± 1.27 | < 0.01 | 1.01(0.28)** | 2.02(0.28)** | 1.02(0.28)** | 5.85 ± 0.99 | 4.14 ± 1.47 | 2.67 ± 1.23 | 0.000 | 1.76(0.26)** | 3.22(0.26)** | 1.46(0.26)** |
6 | 4.80 ± 0.80 | 4.22 ± 1.05 | 4.52 ± 1.11 | 0.06 | 0.69 ± 1.16 | 1.02 ± 1.13 | 1.22 ± 1.49 | 0.11 | −0.36(0.27) | −0.56(0.26) | − 0.20(0.26) | 0.58 ± 0.87 | 1.04 ± 1.14 | 1.30 ± 1.49 | 0.071 | −0.46(0.24) | − 0.72(0.25) | − 0.26(0.24) |
7 | 0.71 ± 1.22 | 1.00 ± 1.32 | 0.92 ± 1.29 | 0.38 | 0.71 ± 1.22 | 1.02 ± 1.33 | 0.94 ± 1.31 | 0.35 | −0.47(0.26) | −0.38(0.26) | 0.09(0.25) | 0.67 ± 1.22 | 1.02 ± 1.35 | 0.93 ± 1.34 | 0.16 | −0.42(0.27) | −0.34(0.27) | 0.09(0.27) |
8 | 5.84 ± 0.46 | 5.78 ± 0.51 | 5.82 ± .059 | 0.30 | 0.71 ± 1.64 | 0.70 ± 1.43 | 1.29 ± 1.72 | 0.12 | −0.067(0.30) | −0.65(0.31) | − 0.59(0.30) | 0.58 ± 1.30 | 0.69 ± 1.44 | 1.30 ± 1.76 | 0.19 | −0.07(0.31) | −0.69(0.32) | − 0.60(0.31) |
9 | 2.80 ± 0.89 | 2.86 ± 0.89 | 2.70 ± 1.04 | 0.68 | 5.86 ± 1.90 | 3.88 ± 2.45 | 3.63 ± 2.62 | < 0.01 | 1.76(0.46)** | 2.01(0.46)** | 0.26(0.46) | 5.29 ± 1.45 | 3.78 ± 1.43 | 2.28 ± 1.28 | 0.00 | 1.58(0.29)** | 3.10(0.29)** | 1.52(0.29)** |
10 | 2.31 ± 1.49 | 2.33 ± 1.61 | 2.76 ± 1.42 | 0.24 | 3.82 ± 2.59 | 1.64 ± 2.07 | 0.93 ± 1.75 | < 0.01 | 2.35(0.44)** | 3.05(0.44)** | 0.70(0.43) | 4.29 ± 2.08 | 2.38 ± 1.86 | 1.96 ± 1.81 | 0.00 | 1.95(0.40)** | 2.38(0.40)** | 0.43(0.40) |
11 | 2.98 ± 1.01 | 3.01 ± 0.88 | 2.98 ± 0.84 | 0.95 | 5.10 ± 1.81 | 3.76 ± 2.55 | 2.00 ± 2.02 | < 0.01 | 1.124(0.44)* | 2.88(0.44)** | 1.74(0.43)** | 5.54 ± 1.37 | 4.16 ± 2.24 | 2.21 ± 1.95 | 0.00 | 1.35(0.39) | 3.24(0.40)** | 1.89(0.39)** |
12 | 1.90 ± 1.36 | 1.86 ± 1.31 | 1.82 ± 1.48 | 0.96 | 1.84 ± 1.33 | 1.86 ± 1.32 | 1.63 ± 1.47 | 0.66 | 0.05(0.28) | 0.28(0.28) | 0.23(0.28) | 4.85 ± 1.20 | 4.93 ± 1.17 | 5.06 ± 1.34 | 0.87 | −0.10(.26) | −0.24(0.26) | 0.14(0.26) |