|
Gene
|
Polymorphism
|
Reference Allele Freq
|
Heterozygote
|
Alt
|
MAF
|
|---|
|
ACE [25, 26]
|
Ins/Del (rs4646994)
|
25%
|
54%
|
21%
|
48%
|
|
ADRB2 [27, 28]
|
Arg16Gly (rs1042713)
|
43%
|
39%
|
18%
|
38%
|
|
ADRB2 [27, 28]
|
Gln27Glu (rs1042714)
|
44%
|
44%
|
11%
|
34%
|
|
APOC3 [29]
|
C3175G (rs5128)
|
69%
|
25%
|
7%
|
19%
|
|
APOA2 [30, 31]
|
-265 T > C (rs5082)
|
28%
|
44%
|
28%
|
50%
|
|
CAT [32]
|
C-262 T (rs1001179)
|
56%
|
41%
|
3%
|
24%
|
|
CYP1A2 [10, 33]
|
-163A > C (rs762551)
|
43%
|
41%
|
16%
|
37%
|
|
EPHX1 [34, 35]
|
Tyr113His (rs1051740)
|
51%
|
38%
|
11%
|
30%
|
|
FABP2 [36]
|
Ala54Thr (rs1799883)
|
54%
|
43%
|
3%
|
25%
|
|
FTO [30, 37]
|
A/T (rs9939609)
|
21%
|
52%
|
26%
|
48%
|
|
GPX1 [38]
|
Pro198Leu (rs1050450)
|
57%
|
43%
|
0%
|
21%
|
|
GSTT1 [39, 40]
|
Ins/Del
|
61%
|
39%
| | |
|
GSTM1 [39, 40]
|
Ins/Del
|
28%
|
72%
| | |
|
HLA-DQ [41]
|
rs2395182_DQA1201
|
93%
|
7%
|
0%
|
3%
|
|
rs7775228_DQB1202
|
72%
|
28%
|
0%
|
14%
|
|
rs2187668_DQ25
|
74%
|
26%
|
0%
|
13%
|
|
rs4639334_DQ7
|
72%
|
20%
|
8%
|
18%
|
|
rs4713586_DQ4
|
100%
|
0%
|
0%
|
0%
|
|
rs7454108_DQ8
|
89%
|
11%
|
0%
|
6%
|
|
IL6 [42, 43]
|
G-174C (rs1800795)
|
49%
|
41%
|
10%
|
30%
|
|
LCT [44]
|
−13,910-CT (rs4988235)
|
53%
|
42%
|
5%
|
26%
|
|
LPL [45]
|
C1595G (rs328)
|
74%
|
23%
|
3%
|
15%
|
|
MTHFR [9, 13]
|
C677T (rs1801133)
|
33%
|
49%
|
18%
|
43%
|
|
PPARG [46, 47]
|
Pro12Ala (rs1801282)
|
84%
|
15%
|
2%
|
9%
|
|
SOD2 [12]
|
C-28 T (rs4880)
|
26%
|
54%
|
20%
|
47%
|
|
TCF7L2 [11, 48]
|
C/T (rs7903146)
|
52%
|
43%
|
5%
|
26%
|
|
TNF [49, 50]
|
G-308A (rs1800629)
|
62%
|
36%
|
2%
|
20%
|
|
VDR [51, 52]
|
C > T (taq1) (rs1544410)
|
39%
|
38%
|
23%
|
42%
|
