Table 1 Gene and polymorphisms tested in the low-GI nutrigenetic patient group
Gene | Polymorphism | Reference Allele Freq | Heterozygote | Alt | MAF |
|---|---|---|---|---|---|
Ins/Del (rs4646994) | 25% | 54% | 21% | 48% | |
Arg16Gly (rs1042713) | 43% | 39% | 18% | 38% | |
Gln27Glu (rs1042714) | 44% | 44% | 11% | 34% | |
APOC3 [29] | C3175G (rs5128) | 69% | 25% | 7% | 19% |
-265 T > C (rs5082) | 28% | 44% | 28% | 50% | |
CAT [32] | C-262 T (rs1001179) | 56% | 41% | 3% | 24% |
-163A > C (rs762551) | 43% | 41% | 16% | 37% | |
Tyr113His (rs1051740) | 51% | 38% | 11% | 30% | |
FABP2 [36] | Ala54Thr (rs1799883) | 54% | 43% | 3% | 25% |
A/T (rs9939609) | 21% | 52% | 26% | 48% | |
GPX1 [38] | Pro198Leu (rs1050450) | 57% | 43% | 0% | 21% |
Ins/Del | 61% | 39% | |||
Ins/Del | 28% | 72% | |||
HLA-DQ [41] | rs2395182_DQA1201 | 93% | 7% | 0% | 3% |
rs7775228_DQB1202 | 72% | 28% | 0% | 14% | |
rs2187668_DQ25 | 74% | 26% | 0% | 13% | |
rs4639334_DQ7 | 72% | 20% | 8% | 18% | |
rs4713586_DQ4 | 100% | 0% | 0% | 0% | |
rs7454108_DQ8 | 89% | 11% | 0% | 6% | |
G-174C (rs1800795) | 49% | 41% | 10% | 30% | |
LCT [44] | −13,910-CT (rs4988235) | 53% | 42% | 5% | 26% |
LPL [45] | C1595G (rs328) | 74% | 23% | 3% | 15% |
C677T (rs1801133) | 33% | 49% | 18% | 43% | |
Pro12Ala (rs1801282) | 84% | 15% | 2% | 9% | |
SOD2 [12] | C-28 T (rs4880) | 26% | 54% | 20% | 47% |
C/T (rs7903146) | 52% | 43% | 5% | 26% | |
G-308A (rs1800629) | 62% | 36% | 2% | 20% | |
C > T (taq1) (rs1544410) | 39% | 38% | 23% | 42% |