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Table 1 Gene and polymorphisms tested in the low-GI nutrigenetic patient group

From: A comparison of a ketogenic diet with a LowGI/nutrigenetic diet over 6 months for weight loss and 18-month follow-up

Gene Polymorphism Reference Allele Freq Heterozygote Alt MAF
ACE [25, 26] Ins/Del (rs4646994) 25% 54% 21% 48%
ADRB2 [27, 28] Arg16Gly (rs1042713) 43% 39% 18% 38%
ADRB2 [27, 28] Gln27Glu (rs1042714) 44% 44% 11% 34%
APOC3 [29] C3175G (rs5128) 69% 25% 7% 19%
APOA2 [30, 31] -265 T > C (rs5082) 28% 44% 28% 50%
CAT [32] C-262 T (rs1001179) 56% 41% 3% 24%
CYP1A2 [10, 33] -163A > C (rs762551) 43% 41% 16% 37%
EPHX1 [34, 35] Tyr113His (rs1051740) 51% 38% 11% 30%
FABP2 [36] Ala54Thr (rs1799883) 54% 43% 3% 25%
FTO [30, 37] A/T (rs9939609) 21% 52% 26% 48%
GPX1 [38] Pro198Leu (rs1050450) 57% 43% 0% 21%
GSTT1 [39, 40] Ins/Del 61% 39%   
GSTM1 [39, 40] Ins/Del 28% 72%   
HLA-DQ [41] rs2395182_DQA1201 93% 7% 0% 3%
rs7775228_DQB1202 72% 28% 0% 14%
rs2187668_DQ25 74% 26% 0% 13%
rs4639334_DQ7 72% 20% 8% 18%
rs4713586_DQ4 100% 0% 0% 0%
rs7454108_DQ8 89% 11% 0% 6%
IL6 [42, 43] G-174C (rs1800795) 49% 41% 10% 30%
LCT [44] −13,910-CT (rs4988235) 53% 42% 5% 26%
LPL [45] C1595G (rs328) 74% 23% 3% 15%
MTHFR [9, 13] C677T (rs1801133) 33% 49% 18% 43%
PPARG [46, 47] Pro12Ala (rs1801282) 84% 15% 2% 9%
SOD2 [12] C-28 T (rs4880) 26% 54% 20% 47%
TCF7L2 [11, 48] C/T (rs7903146) 52% 43% 5% 26%
TNF [49, 50] G-308A (rs1800629) 62% 36% 2% 20%
VDR [51, 52] C > T (taq1) (rs1544410) 39% 38% 23% 42%