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Table 5 Differences in cardiometabolic parameters between both groups at different time points. All data are reported as mean (95% CI)

From: A comparison of a ketogenic diet with a LowGI/nutrigenetic diet over 6 months for weight loss and 18-month follow-up

  Total Cholesterol (mg/dl) HDL Cholesterol (mg/dl) Fasting blood glucose (mg/dl)
Ketogenic Low-GI Nutrigenetic P Ketogenic Low-GI Nutrigenetic P Ketogenic Low-GI Nutrigenetic P
Baseline 245.6 (234.8–256.5) 242.0 (235.0–249.0) 0.56 45.1 (43.4–46.8) 47.6 (46.4–48.8) 0.16 120.5 (119.4–121.5) 105.7 (103.5–108.0) < 0.0001
24 weeks 185.8 (181.4–190.2) 210.3 (205.5–215.0) < 0.0001 54.1 (52.8–55.4) 55.2 (54.3–56.0) 0.182 98.2 (96.7–99.5) 87.0 (85.6–88.3) < 0.0001
2 years 210.2 (204.7–215.7) 189.4 (187.7–191.1) < 0.0001 49.8 (48.8–50.9) 59.5 (59.1–60.0) < 0.0001 106.8 (104.4–109.1) 81.1 (80.2–81.8) < 0.0001
Mean % Change at 2 years from baseline − 13.0% (− 16.0 to − 10.0%) −20.9% (− 22.8 to − 19.0%) < 0.0001 11.6% (8.7–14.5%) 26.1% (23.3–29.1%) < 0.0001 −11.3% (− 13.2 to − 9.4%) −22.9% (− 24.3 to − 21.7%) < 0.0001
  1. Data were analysed using ANCOVA, with significance set at p < 0.05 for primary observations and p < 0.001 for secondary observations