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Table 1 Baseline Demographics, Participant Characteristics, and AHEI Baseline and Year 1 Scores by treatment arm

From: Diet quality, weight loss, and diabetes incidence in the Diabetes Prevention Program (DPP)

 

All

ILS

Metformin

Placebo

p-value

N = 2914

N = 964

N = 977

N = 973

 

Demographics

 Age (years)

50.8 ± 10.6

50.7 ± 11.1

51.3 ± 10.3

50.5 ± 10.3

0.249

 Female

1967 (67.5%)

657 (68.2%)

637 (65.2%)

673 (69.2%)

0.151

 Race/ethnicity

    

0.379

  % Caucasian

1614 (55.4%)

535 (55.5%)

548 (56.1%)

531 (54.6%)

 

  % African American

564 (19.4%)

172 (17.8%)

200 (20.5%)

192 (19.7%)

 

  % Hispanic

460 (15.8%)

157 (16.3%)

151 (15.5%)

152 (15.6%)

 

  % American Indian

154 (5.3%)

50 (5.2%)

49 (5.0%)

55 (5.7%)

 

  % Asian

122 (4.2%)

50 (5.2%)

29 (3.0%)

43 (4.4%)

 

 Education (years)

14.8 ± 3.1

14.8 ± 3.1

14.9 ± 3.1

14.7 ± 3.2

0.579

 Current Smoker

181 (6.2%)

50 (5.2%)

61 (6.2%)

70 (7.2%)

0.187

 Family History of Diabetes

2018 (69.3%)

665 (69.1%)

674 (69.0%)

679 (69.9%)

0.899

 Hypertensiona

832 (28.6%)

272 (28.2%)

288 (29.5%)

272 (28.0%)

0.728

Characteristics

 BMI (kg/m2)

33.9 ± 6.6

33.8 ± 6.7

33.8 ± 6.6

34.2 ± 6.7

0.369

 Waist (cm)

105.1 ± 14.4

104.9 ± 14.7

104.9 ± 14.4

105.3 ± 14.2

0.760

 Waist-to-Hip

0.92 ± 0.09

0.92 ± 0.09

0.93 ± 0.09

0.92 ± 0.08

0.360

 Fasting Glucose (mg/dl)

106.4 ± 8.2

106.3 ± 8.1

106.4 ± 8.4

106.6 ± 8.2

0.772

 2-Hour Glucose (mg/dl)

164.6 ± 17.0

164.3 ± 16.8

165.0 ± 17.2

164.4 ± 17.1

0.670

 HbA1c (%)

5.9 ± 0.5

5.9 ± 0.5

5.9 ± 0.5

5.9 ± 0.5

0.798

 Total daily energy intake (kcal)

1901.4 [1459.8, 2565.4]

1911.1 [1445.7, 2513.3]

1916.0 [1485.2, 2607.3]

1878.2 [1445.1, 2559.0]

0.354

 Leisure MET hrs per week

9.9 [3.9, 20.7]

9.9 [3.8, 21.3]

10.1 [4.0, 20.8]

9.5 [4.0, 19.4]

0.713

AHEI Scores

 DPP Baseline

44.2 ± 10.4

44.4 ± 10.5

43.8 ± 10.3

44.4 ± 10.5

0.327

 DPP Year 1 (Y01)

46.4 ± 10.2

48.6 ± 10.0

45.0 ± 10.0

45.9 ± 10.3

<.001

 Difference Baseline to Year 1

2.3 ± 8.8

4.2 ± 9.0

1.2 ± 8.5

1.4 ± 8.4

<.001

  1. Abbreviations: AHEI Alternative Healthy Eating Index, BMI Body Mass Index, DPP Diabetes Prevention Program, HbA1c Hemoglobin A1c, ILS Intensive lifestyle intervention, MET Metabolic Equivalent
  2. Data are n (%), mean ± SD, or median [Q1, Q3]
  3. aHypertension is defined as meeting any of three criteria: SBP ≥140 mmHg, diastolic blood pressure (DBP) ≥90 mmHg, or taking medications that lower blood pressure