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Table 3 Dietary selenium-calcium interplay in the risk of colorectal cancer (CRC). Stratum specified odds ratios with 95% confidence intervals for multivariable logistic regressiona which includes a considered exposure (dietary selenium intake) and an effect modifier (dietary calcium intake)

From: Calcium intake may explain the reduction of colorectal cancer odds by dietary selenium - a case-control study in Poland

Calcium Selenium

< 1000 mg/day

1000 to < 1500 mg/day

> = 1500 mg/day

< 60 μg/day

1 (ref.)

0.711 (0.408–1.237)

1.109 (0.306–4.016)

60 to < 80 μg/day

0.634 (0.435–0.923)

0.767 (0.433–1.358)

0.296 (0.091–0.959)

≥80 μg/day

0.419 (0.211–0.830)

0.452 (0.225–0.908)

0.091 (0.025–0.328)

  1. aadjusted for age [years], sex, BMI [kg/m2], pure alcohol consumption [g/week], average adult lifetime leisure-time physical activity [METs-h/week], smoking (non smoker, past smoker, current smoker), fish consumption [yes/no], total dietary fibre [g/day], vitamin C [mg/day] and vitamin E [mg/day], taking mineral supplements [yes/no]