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Table 4 Myostatin and follistatin concentrations in older adults consuming the DASH diet for 12 weeks

From: Decreased myostatin in response to a controlled DASH diet is associated with improved body composition and cardiometabolic biomarkers in older adults: results from a controlled-feeding diet intervention study

 

Weeks of Intervention

Variable

0

3

6

9

12

p-value

Myostatin (ng/mL)

3.4 (1.7)*

3.0 (1.5)*

2.9 (1.2)*

2.9 (1.3)*

2.8 (1.1)*

0.006

Follistatin (ng/mL)

1.7 (0.44)

1.6 (0.47)

1.6 (0.48)

1.6 (0.41)

1.7 (0.55)

0.130

Myostatin:Follistatin Ratio

2.12 (1.17)*

2.01 (1.17)

1.96 (0.92)

1.96 (1.11)

1.77 (0.87)*

< 0.001

  1. Data are presented as means and standard deviations. Linear mixed models with fixed effect of Time wks 0, 3, 6, 9, 12 and random subject and intercept for each participant was used to determine changes in the primary outcome variables across the intervention. *p < 0.05 versus baseline