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Table 3 Summary of findings

From: The mean platelet volume and atherosclerotic cardiovascular-risk factors in adults with obesity: a systematic review and meta-analysis of observational studies

Mean platelet volume in individuals with obesity compared to non-obese individuals

Patient or population: Class I and Class II Obesity

Setting: Outpatient

Intervention: None

Comparison: Individuals with Normal Body weights

Outcomes

Absolute effects* (95% CI)

Relative effect

(95% CI)

№ of participants

(studies)

Certainty of the evidence

(GRADE)

Comments

Basal

SMD

Mean Platelet Volume (MPV) Scale from: 6.5 to 12.0

8.5

(7.49–9.51)

0.79

(0.42–1.16)

Higher

(0.42 higher to 1.16 higher) -

1577

(9 observational studies)

MODERATEa

The MPV is increased in individuals with obesity when compared to non-obese individuals

GRADE Working Group grades of evidence

High certainty: We are very confident that the true effect lies close to that of the estimate of the effect

Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different

Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect

Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

  1. CI Confidence interval; SMD Standardised mean difference
  2. *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI)