Parameter | TAD | DGA | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Week 0 | Week 8 | Week 0 | Week 8 | |||||||||
Serum | ||||||||||||
 TNF-α (pg/mL) | 1.99 | ± | 0.127 | 2.20 | ± | 0.150 | 2.23 | ± | 0.213 | 2.23 | ± | 0.214 |
 IL-10 (pg/mL) | 0.283 | ± | 0.0227 | 0.286 | ± | 0.0181 | 0.529 | ± | 0.146 | 0.840 | ± | 0.441 |
 IL-1β (pg/mL) | 0.121 | ± | 0.0128 | 0.125 | ± | 0.0176 | 0.122 | ± | 0.009 | 0.125 | ± | 0.008 |
  IL-6 (pg/mL) | 1.46 | ± | 0.293 | 1.90 | ± | 0.403 | 1.45 | ± | 0.289 | 1.35 | ± | 0.255 |
 IL-8 (pg/mL) | 4.02 | ± | 0.339 | 4.57 | ± | 0.335 | 6.22 | ± | 0.677 | 7.19 | ± | 1.23 |
 IP-10 (pg/mL) | 579 | ± | 135 | 569 | ± | 116 | 698 | ± | 165 | 1450 | ± | 593 |
 Eotaxin (pg/mL) | 124 | ± | 14.7 | 160 | ± | 34.3 | 155 | ± | 20.8 | 143 | ± | 11.4 |
 MCP-1 (pg/mL) | 105 | ± | 9.21 | 113 | ± | 12.4 | 112 | ± | 6.84 | 115 | ± | 8.83 |
 MDC (pg/mL) | 962 | ± | 80.6 | 1045 | ± | 107 | 901 | ± | 71.8 | 981 | ± | 60.3 |
 MMP-1 (pg/mL) | 2.47 | ± | 0.392 | 2.28 | ± | 0.313 | 2.49 | ± | 0.509 | 2.50 | ± | 0.408 |
 MMP-3 (pg/mL) | 9.60 | ± | 0.875 | 8.80 | ± | 0.815 | 9.70 | ± | 1.03 | 11.1 | ± | 1.13 |
 MMP-9 (pg/mL) | 44.1 | ± | 6.70 | 45.2 | ± | 9.48 | 31.2 | ± | 3.2 | 33.9 | ± | 4.03 |
 CRP (mg/L) | 8.05 | ± | 1.53 | 9.37 | ± | 1.60 | 10.6 | ± | 2.85 | 6.90 | ± | 1.18 |
 SAA (mg/L) | 13.9 | ± | 4.89 | 11.0 | ± | 2.43 | 22.3 | ± | 9.9 | 9.69 | ± | 2.08 |
 sICAM1 (ng/mL) | 552 | ± | 40.5 | 565 | ± | 29.3 | 611 | ± | 41.2 | 593 | ± | 48.4 |
 sVCAM1 (ng/mL) | 551 | ± | 33.8 | 574 | ± | 29.8 | 644 | ± | 34.2 | 632 | ± | 37.5 |
PBMCs | ||||||||||||
 CD3/28-IL-10 (pg/mL) | 313 | ± | 59.2 | 285 | ± | 77.8 | 504 | ± | 67.8 | 439 | ± | 76.4 |
 CD3/28-IL-13 (pg/mL) | 62.3 | ± | 11.2 | 52.8 | ± | 10.7 | 68.9 | ± | 8.88 | 75.0 | ± | 7.52 |
 CD3/28-IL-17A (pg/mL) | 610 | ± | 133 | 613 | ± | 140 | 651 | ± | 101 | 856 | ± | 137 |
 CD3/28-IL-2 (pg/mL) | 651 | ± | 140 | 917 | ± | 289 | 689 | ± | 130 | 1020.0 | ± | 187 |
 CD3/28-IFNγ (pg/mL) | 111 | ± | 22.5 | 86.1 | ± | 18.0 | 156 | ± | 21.9 | 129 | ± | 18.6 |
 LPS-IL-10 (pg/mL) | 103 | ± | 34.5 | 131 | ± | 28.6 | 124 | ± | 24.6 | 147 | ± | 34.9 |
 LPS-IL-1b (pg/mL) | 438 | ± | 129 | 329 | ± | 108 | 370 | ± | 92.5 | 280 | ± | 76.4 |
 LPS-IL-6 (pg/mL) | 0.480 | ± | 0.247 | 0.571 | ± | 0.305 | 0.468 | ± | 0.312 | 0.313 | ± | 0.153 |
 LPS-TNF- α (pg/mL) | 361 | ± | 91.2 | 353 | ± | 93.2 | 317 | ± | 57.5 | 448 | ± | 166 |