Table 2 Demographic characteristics, biochemical indices, nutritional status and Illness severity of the COVID-19 patients in intensive care unit

Sex (frequency (percent))

Male

83 (40.7%)

45 (44.1%)

38 (37.3%)

0.318

Female

121 (59.3%)

57 (55.9%)

64 (62.7%)

Age (year)(Mean ± SD)

61.98 ± 15.27

63.62 ± 14.07

60.34 ± 16.28

0.125

APACHE2^a

15.22±6.80

16.63±6.97

13.81±6.36

.003

SOFA^a

5.65±2.96

6.42±3.07

4.89±2.64

<0.001

Duration of hospitalization (day)^a 

14.99 ± 9.31

12.21 ±8.43

17.76 ± 9.36

<0.001

Duration of hospitalization in ICU (day)^a

11.04 ± 7.93

8.28 ± 7.36

13.81 ±7.54

<0.001

Comorbidities(frequency (percent))

No

75 (36.8%)

33 (32.4%)

42 (41.2%)

0.470

Yes

Total

129 (63.2%)

69 (67.6%)

60 (58.8%)

Diabetes

21 (10.3%)

8 (7.8%)

13 (12.7%)

Hypertension

19 (9.3%)

10 (9.8%)

9 (8.8%)

Cancer

5 (2.5%)

3 (2.9%)

2 (2.0%)

Diabetes-hypertension

26 (12.7%)

12 (11.8%)

14 (13.7%)

IHD

20 (9.8%)

13 (12.7%)

7 (6.9%)

IHD-hypertension

9 (4.4%)

6 (5.9%)

3 (2.9%)

Renal

14 (6.9%)

10 (9.8%)

4 (3.9%)

Brain

5 (2.5%)

3 (2.9%)

2 (2.0%)

Others

10 (4.9%)

4 (3.9%)

6 (5.9%)

NUTRIC Score^a

4.08±1.58

4.46±1.38

3.71±1.68

.001

Albumin (g/dl)^a

3.38±0.47

3.40±0.49

3.36±0.45

0.527

ALT (IU/L)^a

58.38± 85.20

52.14+43.64

64.62± 112.28

0.297

AST (IU/L)^a

68.81 ± 80.39

71.81± 86.50

65.80± 90.98

0.595

Bilirubin total (mg/dl)^a

0.86± 0.85

0.81± 0.46

0.92± 1.11

.391

Bilirubin direct (mg/dl)^a

0.31± 0.42

0.27± 0.14

0.34± 0.57

.276

LDH (U/L)^a

966.32± 462.11

973.33± 446.45

959.31± 479.35

.829

CPK (U/L)^a

376.56± 622.58

398.72± 569.93

354.41± 673.24

.612

CRP (mg/L)^a

75.55± 37.23

81.56± 39.31

69.53± 34.18

.021

PaO2 (mmHg)^a

53.32± 27.90

51.61± 27.77

55.03± 28.06

.382

INR^a

1.29 ± 0.44

1.34±0.59

1.25±0.19

.114

PH^a

7.34±0.10

7.31±0.10

7.36±0.08

<0.001

PCO2 (mmHg)^a

41.20±11.95

43.68±14.15

38.72±8.64

.003

Illness severity(frequency(percent))^b

mild

13 (6.4%)

2 (2.0%)

11 (10.8%)

.021

Moderate

54 (26.5%)

25 (24.5%)

29 (28.4%)

Severe

137 (67.2%)

75 (73.5%)

62 (60.8%)