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Table 2 hs-CRP and Hcy changes from baseline to 1 year in evaluable participants (CCA)

From: Exploratory analysis of the effect of a controlled lifestyle intervention on inflammatory markers – the Healthy Lifestyle Community Programme (cohort 2)

Parameters

hs-CRP, mg/l

Hcy, µmol/l

Apn, µg/ml

Group

IN (n = 70)

CON (n = 34)

IN (n = 68)

CON (n = 52)

IN (n = 80)

CON (n = 61)

Mean

SEM or 95% CI

Mean

SEM or 95% CI

Mean

SEM or 95% CI

Mean

SEM or 95% CI

Mean

SEM or 95% CI

Mean

SEM or 95% CI

Baseline

1.3

0.2

2.6

0.7

12.4

0.4

11.8

0.4

10.5

0.6

7.7

0.6

10 weeks

0.9

0.1

3.0

0.8

12.3

0.4

12.2

0.4

8.0

0.4

7.9

0.7

6 months

1.0

0.1

2.6

0.6

-

 

-

   

1 year

1.0

0.2

2.1

0.6

11.4

0.4

10.4

0.4

-

-

Δ(baseline, 1 year)

-0.3

-0.7, 0.1

-0.5

-1.7, 0.8

-1.0

-1.8,

-0.1

-1.4

-2.0,

-0.8

-

-

p WG *

0.002 a

0.735 a

0.060 a

 < 0.001 b

 < 0.001 a

0.595 a

p BG †

0.001 c

0.439 c

0.004 c

p BG † (multivariable-adjusted)

0.001 d

0.912 d

0.002 f

0.006 e

0.825 e

0.003 g

  1. CCA Complete case analysis, hs-CRP High-sensitivity C-reactive protein, Hcy Homocysteine, Apn Adiponectin, IN Intervention, CON Control, SEM Standard error of the mean, CI Confidence interval, p WG p-values for within-group changes from baseline to 1 year, p BG p-values for between-group differences in 1-year trajectories, BMI Body mass index;
  2. * p-value for within-group comparisons by:
  3. a Wilcoxon test (two-sided)
  4. b paired t-test (two-sided)
  5. † p-value for between-group comparisons by:
  6. c repeated measures ANCOVA, adjusted for the baseline values of the respective parameters
  7. d repeated measures ANCOVA, adjusted for baseline values (hs-CRP and Hcy, respectively) as well as baseline age, sex, education level, marital status, smoker status, alcohol intake, BMI, and HbA1c
  8. e repeated measures ANCOVA, adjusted for baseline values (hs-CRP and Hcy, respectively), baseline age, sex, education level, marital status as well as changes (Δ[baseline, 1 year]) in smoker status, alcohol intake, BMI, and HbA1c
  9. f one-way ANCOVA, adjusted for the baseline Apn, age, sex, education level, marital status, alcohol intake, smoker status, BMI, TC, HDL-C, insulin, diastolic BP, and RHR
  10. g one-way ANCOVA, adjusted for the baseline Apn, age, sex, education level, marital status, and changes in alcohol intake, smoker status, BMI, TC, HDL-C, insulin, diastolic BP, and RHR