Exploratory analysis of the effect of a controlled lifestyle intervention on inflammatory markers – the Healthy Lifestyle Community Programme (cohort 2)

Koeder, Christian; Anand, Corinna; Husain, Sarah; Kranz, Ragna-Marie; Schoch, Nora; Alzughayyar, Dima; Bitterlich, Norman; Hahn, Andreas; Englert, Heike

doi:10.1186/s40795-023-00684-2

Table 3 Bivariate correlations of changes in hs-CRP, Hcy, and Apn with changes in other markers

From: Exploratory analysis of the effect of a controlled lifestyle intervention on inflammatory markers – the Healthy Lifestyle Community Programme (cohort 2)

Parameter changes	Correlations with hs-CRP change (Δ[baseline, 1 year])			Correlations with Hcy change (Δ[baseline, 1 year])			Correlations with Apn change (Δ[baseline, 10 weeks])
Parameter changes	r (CI)	p-value	n	r (CI)	P value	n	r (CI)	p-value	n
Body weight	0.231 (0.038; 0.408)	0.018	104	-0.132 (-0.305; 0.049)	0.152	120	0.254 (0.090; 0.405)	0.002	141
BMI	0.241 (0.048; 0.417)	0.014	104	-0.130 (-0.303; 0.051)	0.156	120	0.267 (0.103; 0.416)	0.001	141
WC	0.415 (0.234; 0.568)	< 0.001	104	-0.163 (-0.334; 0.019)	0.077	119	0.256 (0.092; 0.406)	0.002	141
Systolic BP	0.031 (-0.163; 0.222)	0.755	104	0.065 (-0.116; 0.242)	0.479	120	0.064 (-0.103; 0.228)	0.449	140
Diastolic BP	-0.075 (-0.264; 0.120)	0.448	104	0.006 (-0.173; 0.185)	0.945	120	0.183 (0.016; 0.340)	0.031	140
Pulse pressure	0.070 (-0.125; 0.259)	0.483	104	0.073 (-0.108; 0.249)	0.426	120	0.002 (-0.164; 0.168)	0.982	140
RHR	0.077 (-0.118; 0.266)	0.438	104	-0.100 (-0.275; 0.081)	0.276	120	0.019 (-0.147; 0.184)	0.821	140
TC	0.010 (-0.183; 0.202)	0.923	104	-0.009 (-0.188; 0.171)	0.923	120	0.251 (0.087; 0.402)	0.003	141
LDL-C (meas.)	-0.035 (-0.226; 0.159)	0.726	104	0.003 (-0.176; 0.182)	0.977	120	0.159 (-0.008; 0.317)	0.059	141
LDL-C (calc.)	0.029 (-0.165; 0.221)	0.767	103	-0.033 (-0.212; 0.148)	0.720	119	0.200 (0.034; 0.356)	0.018	140
non-HDL-C	0.045 (-0.149; 0.236)	0.653	104	-0.048 (-0.225; 0.132)	0.601	120	0.251 (0.087; 0.402)	0.003	141
REM-C	0.191 (-0.003; 0.372)	0.052	104	-0.186 (-0.355; -0.005)	0.041	120	0.203 (0.037; 0.358)	0.016	141
HDL-C	-0.138 (-0.323; 0.057)	0.161	104	0.075 (-0.106; 0.251)	0.416	120	0.133 (-0.034; 0.293)	0.115	141
TAG	0.137 (-0.058; 0.322)	0.167	104	-0.133 (-0.306; 0.048)	0.148	120	0.092 (-0.075; 0.254)	0.280	141
Glucose	0.216 (0.022; 0.394)	0.028	104	-0.083 (-0.259; 0.098)	0.370	120	-0.071 (-0.234; 0.096)	0.405	141
HbA1c	0.131 (-0.064; 0.316)	0.185	104	0.136 (-0.045; 0.308)	0.137	120	0.104 (-0.063; 0.265)	0.219	141
Insulin	0.066 (-0.128; 0.256)	0.503	104	-0.051 (-0.228; 0.130)	0.582	120	0.174 (0.008; 0.331)	0.039	141
hs-CRP	-	-	-	-	-	-	0.122 (-0.060; 0.296)	0.187	119
Hcy	-0.264 (-0.448; -0.059)	0.011	92	-	-	-	-0.052 (-0.216; 0.114)	0.542	141
PDI	-0.045 (-0.239; 0.153)	0.660	100	0.110 (-0.076; 0.289)	0.244	114	-0.178 (-0.342; -0.004)	0.044	129
hPDI	0.042 (-0.156; 0.237)	0.676	100	-0.064 (-0.245; 0.122)	0.497	114	-0.195 (-0.357; -0.021)	0.027	129
uPDI	-0.006 (-0.202; 0.191)	0.956	100	-0.116 (-0.294; 0.070)	0.218	114	0.134 (-0.041; 0.301)	0.130	129

Participants of both the intervention and control groups are combined. hs-CRP High-sensitivity C-reactive protein, Hcy Homocysteine, Apn Adiponectin, r: Spearman correlation coefficients, CI 95% Confidence interval, BMI Body mass index, WC Waist circumference, BP Blood pressure, RHR Resting heart rate, TC Total cholesterol, LDL-C (meas.) Measured LDL cholesterol, LDL-C (calc.) Calculated LDL-C, non-HDL-C Non-HDL cholesterol, REM-C Remnant cholesterol, HDL-C HDL cholesterol, TAG Triglycerides, PDI Plant-based diet index, hPDI Healthful PDI, uPDI Unhealthful PDI

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ISSN: 2055-0928

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