From: Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients
Hemodialysis (n = 35) | Control (n = 17) | P | |
---|---|---|---|
Age,b y | 49 ± 15 | 45 ± 11 | 0.25 |
Race, n (%) | |||
African American | 28 (80) | 11 (65) | |
Caucasian | 7 (20) | 6 (35) | 0.23 |
Male sex, n (%) | 28 (80) | 13 (76) | 0.77 |
Primary Disorder of ESRD, n (%) | |||
Hypertension | 14 (40) | ||
Diabetes Mellitus | 7 (20) | ||
Glomerulonephritis | 7 (20) | ||
RCC Bilateral Nephrectomy | 1 (3) | – | NA |
Polycystic Kidney Disease | 1 (3) | ||
Other | 5 (14) | ||
Dialysis Vintage,c months | 34 (17, 120) | NA | |
Body Composition | |||
BMI,b kg/m2 | 29 ± 6 | 28 ± 7 | 0.34 |
Truncal Fat,b % | 38 ± 13 | 33 ± 12 | 0.09 |
Fat Mass,c kg | 30 (23, 37) | 24 (15, 31) | 0.21 |
Lean Mass,c kg | 52 (49, 61) | 59 (47, 66) | 0.34 |
BUN,b mg/dL | 45 ± 16 | 13 ± 3 | <0.001 |
Creatinine,b mg/dL | 9.7 ± 2.9 | 0.9 ± 0.1 | <0.001 |
Albumin,b g/dL | 3.9 ± 0.4 | 4.0 ± 0.2 | 0.34 |
hs-CRP,c mg/L | 4.0 (1.8, 10.6) | 0.9 (0.4, 3.1) | <0.001 |
Hematocrit,b % | 37 ± 5 | 43 ± 3 | <0.001 |
Fasting Glucose,b mg/dL | 98 ± 17 | 105 ± 23 | 0.11 |
Baseline Insulin,c μU/mL | 12.6 (10.7, 19.8) | 10.4 (5.2, 13.3) | 0.05 |
HbA1c,b % | 5.2 ± 0.6 | 5.3 ± 0.5 | 0.33 |
HOMA-IR,c | 2.9 (2.2, 4.4) | 2.7 (1.1, 3.5) | 0.17 |