Gene/season | rs ID/season | CHR | Position | Allelesa | MAF | Genotypeb | PHWE | Complete case datasetc | Observed subject datasetd | Multiple imputation dataset (m = 100)e | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AA | Aa | aa | β | S.E. | P | β | S.E. | P | β | S.E. | P | |||||||
Cross-sectional studyf | ||||||||||||||||||
 Number of observations (person · season) |  |  |  |  |  |  |  | 51 |  |  | 72 |  |  | 78 |  | |||
 PSRC1 | rs599839 | 1 | 109279544 | A>G | 0.08 | 66 | 11 | 1 | 0.79 | -7.1 × E-2 | 4.0 × E-2 | 0.08 | -8.6 × E-2 | 3.5 × E-2 | 0.01 | -8.0 × E-2 | 3.4 × E-2 | 0.02 |
 HMGCR | rs12654264 | 5 | 75352778 | T>A | 0.44 | 25 | 38 | 15 | 1.00 | 3.5 × E-2 | 3.7 × E-2 | 0.35 | 2.1 × E-2 | 2.9 × E-2 | 0.47 | 2.3 × E-2 | 2.7 × E-2 | 0.40 |
 TIMD4 | rs6882076 | 5 | 156963286 | C>T | 0.15 | 56 | 21 | 1 | 0.82 | -1.9 × E-2 | 3.7 × E-2 | 0.61 | 2.2 × E-2 | 2.8 × E-2 | 0.44 | 1.9 × E-2 | 2.7 × E-2 | 0.50 |
 TBL2 | rs17145738 | 7 | 73568544 | C>T | 0.11 | 62 | 15 | 1 | 1.00 | -5.1 × E-2 | 3.6 × E-2 | 0.17 | -5.5 × E-2 | 2.9 × E-2 | 0.06 | -5.1 × E-2 | 2.9 × E-2 | 0.09 |
 - | rs651007 | 9 | 133278431 | C>T | 0.28 | 37 | 39 | 2 | 0.08 | 5.6 × E-2 | 3.0 × E-2 | 0.06 | 4.8 × E-2 | 2.4 × E-2 | 0.05 | 4.8 × E-2 | 2.4 × E-2 | 0.05 |
 TOMM40 | rs1160985 | 19 | 44900155 | C>T | 0.35 | 32 | 38 | 8 | 0.80 | -5.3 × E-2 | 3.2 × E-2 | 0.11 | -6.4 × E-2 | 2.6 × E-2 | 0.01 | -6.7 × E-2 | 2.5 × E-2 | 0.009 |
 APOC1 | rs445925 | 19 | 44912383 | G>A | 0.10 | 64 | 12 | 2 | 0.35 | -2.0 × E-2 | 4.8 × E-2 | 0.68 | -5.9 × E-2 | 3.3 × E-2 | 0.08 | -5.8 × E-2 | 3.2 × E-2 | 0.07 |
Seasonal variation researchg | ||||||||||||||||||
 Number of observations (person · season) |  |  |  |  |  |  |  | 204 |  |  | 262 |  |  | 312 |  | |||
 PSRC1 | rs599839 |  |  |  |  |  |  |  |  | -4.8 × E-2 | 3.6 × E-2 | 0.19 | -4.8 × E-2 | 3.1 × E-2 | 0.12 | -4.7 × E-2 | 3.2 × E-2 | 0.15 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.5 × E-2 | 8.9 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.08 | -1.1 × E-2 | 1.1 × E-2 | 0.34 | |
 HMGCR | rs12654264 |  |  |  |  |  |  |  |  | 3.9 × E-2 | 3.3 × E-2 | 0.24 | 2.6 × E-2 | 2.4 × E-2 | 0.28 | 2.5 × E-2 | 2.6 × E-2 | 0.33 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.4 × E-2 | 8.9 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.07 | -1.1 × E-2 | 1.1 × E-2 | 0.34 | |
 TIMD4 | rs6882076 |  |  |  |  |  |  |  |  | 6.5 × E-3 | 3.2 × E-2 | 0.84 | 1.8 × E-2 | 2.4 × E-2 | 0.45 | 1.9 × E-2 | 2.6 × E-2 | 0.47 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.4 × E-2 | 8.9 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.07 | -1.1 × E-2 | 1.1 × E-2 | 0.34 | |
 TBL2 | rs17145738 |  |  |  |  |  |  |  |  | -4.6 × E-2 | 3.2 × E-2 | 0.16 | -4.8 × E-2 | 2.6 × E-2 | 0.08 | -4.7 × E-2 | 2.8 × E-2 | 0.09 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.4 × E-2 | 8.9 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.08 | -1.1 × E-2 | 1.1 × E-2 | 0.34 | |
 - | rs651007 |  |  |  |  |  |  |  |  | 5.0 × E-2 | 2.7 × E-2 | 0.07 | 4.7 × E-2 | 2.1 × E-2 | 0.03 | 4.7 × E-2 | 2.3 × E-2 | 0.04 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.11 | -1.5 × E-2 | 8.2 × E-3 | 0.07 | -1.1 × E-2 | 1.1 × E-2 | 0.34 | |
 TOMM40 | rs1160985 |  |  |  |  |  |  |  |  | -4.7 × E-2 | 2.8 × E-2 | 0.11 | -5.9 × E-2 | 2.2 × E-2 | 0.01 | -5.9 × E-2 | 2.4 × E-2 | 0.01 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.11 | -1.6 × E-2 | 7.8 × E-3 | 0.04 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.8 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.07 | -1.1 × E-2 | 1.1 × E-2 | 0.33 | |
 APOC1 | rs445925 |  |  |  |  |  |  |  |  | -1.4 × E-2 | 4.3 × E-2 | 0.74 | -4.9 × E-2 | 2.8 × E-2 | 0.08 | -4.9 × E-2 | 3.0 × E-2 | 0.11 |
 Season | - Winter |  |  |  |  |  |  |  |  | Reference | Reference | Reference | ||||||
- Spring |  |  |  |  |  |  |  |  | -1.5 × E-2 | 8.9 × E-3 | 0.11 | -1.7 × E-2 | 7.8 × E-3 | 0.03 | -1.6 × E-2 | 1.1 × E-2 | 0.13 | |
- Summer |  |  |  |  |  |  |  |  | -2.8 × E-2 | 8.9 × E-3 | 0.002 | -2.4 × E-2 | 7.7 × E-3 | 0.002 | -2.2 × E-2 | 1.1 × E-2 | 0.04 | |
- Autumn |  |  |  |  |  |  |  |  | -1.4 × E-2 | 9.0 × E-3 | 0.12 | -1.5 × E-2 | 8.2 × E-3 | 0.07 | -1.1 × E-2 | 1.1 × E-2 | 0.34 |