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Table 1 Area under the curve (AUC) and 95% confidence interval (CI) of ROC curves when ranges of urine osmolality and urinary creatinine measured on a 24-h collection of urine are used to predict the 24 h urine volume and the 24 h intake of water. All calculations were based on 157 urine collections performed during both normal and increased water consumption

From: Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers

Volume (L)

Osmolality

50–400

Osmolality

50–600

Osmolality

 > 800

Creatinine

2–6

Creatinine

2–9

Creatinine

 > 15

PREDICTION OF URINE VOLUME—analysis of 24 h urine collection

AUC

(95% CI)

0.87

(0.82–0.93)

0.87

(0.81–0.93)

0.89

(0.81–0.97)

0.86

(0.80–0.93)

0.84

(0.78–0.90)

0.92

(0.82–1.00)

Pos./neg

58 / 99

115 / 42

20 / 137

66 / 91

96 / 61

12 / 145

PREDICTION OF WATER INTAKE—analysis of 24-h urine collection

AUC

(95% CI)

0.77

(0.70–0.85)

0.77

(0.69–0.85)

0.74

(0.63–0.85)

0.75

(0.67–0.83)

0.75

(0.67–0.82)

0.81

(0.71–0.90)

Pos./neg

58 / 99

115 / 42

20 / 137

66 / 91

96 / 61

12 / 145

  1. Pos./neg. Number of positive and negative indications, AUC Area under the curve, 95% CI 95% confidence interval