Effects of vitamin B12 supplementation on oxidative stress markers and pro-inflammatory cytokines during pregnancy and postpartum among Bangladeshi mother–child pairs

Table 2 Within group changes in plasma 8-hydroxy-2′-deoxyguanosine (8-OH-dG) and cytokines between baseline and 3 months post-partum

	Placebo (n = 33)	P-value	B12-group (n = 30)	P-value
^a8-OHdG	-0.38 (-1.23, 0.48)	0.376	-1.18 (-2.19, -0.17)	0.023
^aIFN-γ	-0.02 (-0.83, 0.79)	0.962	-0.52 (-1.83, 0.79)	0.423
TNF-α	-0.11(-0.56, 0.35)	0.629	-16.7 (-51.5, 18.1)	0.334
^aIL-10	0.24 (-0.56, 1.04)	0.543	-0.49 (-1.07, 0.09)	0.096
IL-6	-1.08 (-2.50, 0.33)	0.129	-27.8 (-85.1, 29.5)	0.329
IL-4	0.08 (-0.41, 0.57)	0.741	0.73 (-0.76, 2.21)	0.323
^aIL-2	0.08 (-0.24, 0.40)	0.612	0.25 (-0.46, 0.96)	0.478

Data were presented as beta coefficient with 95% confidence interval within parenthesis. Two-way repeated measures ANOVA was used to estimate the P-values and the model was adjusted by mother’s age, BMI, mode of delivery; and infants’ birth weight and sex
^aData were log transformed

ISSN: 2055-0928