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Table 1 Distribution of cohort characteristics, overall and between treatment allocations

From: Weekly cholecalciferol supplementation results in significant reductions in infection risk among the vitamin D deficient: results from the CIPRIS pilot RCT

 

Placebo n = 16 (47.1%)

Treatment n = 18 (52.9%)

Total infections during the study

54

44

Infection type

  

  Respiratory tract infection

32 (59.3)

36 (81.8)

  Gastrointestinal infection

11 (20.4)

5 (11.4)

  Urinary tract infection

0

0

  Skin infection

2 (3.7)

0

  Ear infection

1 (1.9)

0

  Eye infection

0

1 (2.3)

  Cold sore

5 (9.3)

2 (4.6)

  Systemic/nonspecific

3 (5.6)

0

Sex

  

  Male

5 (31.3)

9 (50.0)

  Female

11 (68.8)

9 (50.0)

Birthplace

  

  Australia

15 (88.2)

14 (82.4)

  New Zealand

1 (5.9)

1 (5.9)

  United Kingdom

0

2 (11.8)

  Singapore

1 (5.9)

0

BMI at baseline

  

  < 18.5

1 (6.3)

0

  18.5–24.9

8 (50.0)

10 (55.6)

  25.0–29.9

6 (37.5)

7 (38.9)

  30 or greater

1 (6.3)

1 (5.6)

Taking any medications at baseline?

  

  No

9 (56.3)

9 (50.0)

  Yes

7 (43.8)

9 (50.0)

Taking any supplements at baseline?

  

  No

12 (75.0)

15 (83.3)

  Yes

4 (25.0)

3 (16.7)

Ever smoked?

  

  No

12 (75.0)

15 (83.3)

  Yes

4 (25.0)

3 (16.7)

How much time do you usually spend in the sun on weekends and holidays in summer?

  

  < 30 min/day

1 (6.3)

1 (5.6)

  30–60 min/day

2 (12.5)

3 (16.7)

  1–2 h/day

6 (37.5)

4 (22.2)

  2–3 h/day

5 (31.3)

4 (22.2)

  3–4 h/day

2 (12.5)

4 (22.2)

  4 or more hours/day

0

2 (11.1)

Age

35.0 (12.5; 19–51)

30.3 (11.8; 18–52)

Baseline 25(OH)D (nmol/L)

76.4 (27.3; 36–132)

60.5 (13.9; 32–78)

  1. Results for categorical and dichotomous variables are presented at n (%). Results for age and baseline 25(OH)D are presented as mean (SD; range). Significance of difference in dichotomous or categorical variables between treatment arms is assessed by chi-square test. Significance of difference in continuous variables between treatment arms is assessed by Kruskal-Wallis test.
  2. 25(OH)D 25-hydroxyvitamin D, nmol/L nanomoles per litre.