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Table 2 The impact of consumption of probiotic or control kefir for 4 and 8 weeks on biochemical indices of blood sera in healthy subjects

From: Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults

Indices Probiotic group (PG) Control group (CG) Extent of changes between PG and CG
  Mean (SD)   Mean (SD)   Mean (SD)   Mean (SD)  
   p=    p=    p=    p= p=  
  Baseline 1 4 weeks Baseline 1 vs 4 weeks Baseline 2 8 weeks Baseline 2 vs 8 weeks Baseline 1 4 weeks Baseline 1 vs 4 weeks Baseline 2 8 weeks Baseline 2 vs 8 weeks Baseline 1 to 4 weeks Baseline 2 to 8 weeks
  n 71 n 71   n 43 n 43   n 66 n 66   n 33 n 33    
Total cholesterol (mmol/L) 5.9 (0.7) 6.0 (0.8) 0.259 5.9 (0.9) 5.7 (0.8) 0.257 6.0 (0.8) 6.1 (0.9) 0.364 6.2 (1.0) 6.2 (0.9) 0.031 0.798 0.019
HDL cholesterol (mmol/L) 1.7 (0.5) 1.7 (0.5) 0.943 1.7 (0.4) 1.6 (0.4) 0.229 1.8 (0.5) 1.8 (0.5) 0.001 1.8 (0.5) 1.8 (0.5) 0.385 0.025 0.551
LDL cholesterol (mmol/L) 3.8 (0.7) 3.8 (0.7) 0.083 3.8 (0.7) 3.6 (0.7) 0.001 3.7 (0.8) 3.8 (0.8) 0.822 4.0 (0.8) 4.0 (0.7) 0.736 0.298 0.037
LDL-C/HDL-C 2.5 (0.9) 2.4 (0.9) 0.303 2.5 (0.8) 2.4 (0.8) 0.013 2.2 (0.8) 2.3 (0.8) 0.001 2.3 (0.7) 2.4 (0.7) 0.018 0.014 0.004
Oxidized LDL (U/L) 53.7 (15.1) 50.8 (14.0) ˂0.001 52.7 (14.1) 50.4 (14.4) ˂0.001 50.5 (12.5) 49.6 (12.3) 0.164 51.0 (11.2) 50.8 (11.6) 0.630 0.103 0.0002
Triglycerides (mmol/L) 1.2 (0.7) 1.0 (0.5) 0.005 1.0 (0.4) 1.0 (0.6) 0.033 1.1 (0.5) 1.0 (0.4) 0.165 1.0 (0.4) 1.1 (0.3) 0.507 0.244 0.044
Glucose (mmol/L) 4.8 (0.5) 4.8 (0.5) 0.294 4.8 (0.4) 4.9 (0.6) 0.649 4.6 (0.6) 4.7 (0.6) 0.279 4.7 (0.6) 4.7 (0.6) 0.472 0.834 0.964
HbA1c (%) 5.8 (0.3) 5.5 (0.4) ≤0.001 5.4 (0.2) 5.5 (0.2) ≤0.001 5.7 (0.3) 5.6 (0.3) ≤0.001 5.4 (0.2) 5.4 (0.2) ≤0.001 0.220 0.719
  1. Data represent the mean (standard deviation. BL 1 data were comprised of n = 71 volunteers of PG group and n = 66 volunteers of CG who completed the trial at 4 week; BL 2 data comprised of n = 43 volunteers (PG ) and n = 33 (CG) completing the trial at 8 weeks. Baseline 1 and 2 and intervention data (4 weeks and 8 weeks, resp) were compared with a paired t-test within groups, and extent of changes between PG and CG was compaired with an unpaired t-test