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Table 1 Subject characteristics by supplementation arma,b,g

From: Reduction of parathyroid hormone with vitamin D supplementation in blacks: a randomized controlled trial

Characteristic

Vitamin D3 Dose Assignment (IU)

 

PLACEBO

1,000

2,000

4,000

Overall

(n = 81)

(n = 81)

(n = 83)

(n = 83)

Age (y)

50.7 (44.1-58.0)b

51.1 (43.4-60.1)

50.3 (43.5-58.3)

51.3 (44.1-59.7)

51.0 (43.6-59.4)

Sex, No. (%)

     

 Male

27 (33.3)

22 (27.2)

28 (33.7)

29 (34.9)

106 (32.3)

 Female

54 (66.7)

59 (72.8)

55 (66.3)

54 (65.1)

222 (67.7)

BMI (kg/m2)

31.2 (26.5-35.9)

30.5 (27.0-37.5)

31.9 (26.2-36.9)

31.4 (27.4-35.7)

31.2 (26.8-36.3)

Biomarkers

     

 PTH (pg/mL)

36.75 (30.40-47.20)

35.40 (28.90-47.25)

36.40 (28.95-47.25)

37.40 (29.40-56.40)

36.9 (29.4-49.0)

 25 (OHD) (ng/mL)

15.1 (10.4-23.6)

16.2 (11.0-22.7)

13.9 (9.5-22.3)

15.7 (11.0-23.3)

15.3 (10.4-22.8)

Smoking status, No. (%)

     

 Never

33 (40.7)

36 (44.4)

33 (39.8)

44 (53.0)

146 (44.5)

 Past

20 (24.7)

16 (19.8)

27 (32.5)

20 (24.1)

83 (25.3)

 Current

28 (34.6)

29 (35.8)

23 (27.7)

19 (22.9)

99 (30.2)

Frequency of exercise, (day/week)

3.0 (0.5-5.0)

3.0 (1.0-5.0)

3.0 (0-5.0)

3.0 (0-5.0)

3.0 (0-5.0)

Dietary vitamin D intake (IU)c

147.3 (71.4-262.8)

162.5 (92.6-295.5)

144.0 (58.0-265.1)

198.1(83.2-306.4)

167.5 (72.3-291.8)

Dietary calcium intake (mg)c

277.0 (171.7-632.3)

422.9 (226.1-795.9)

318.8 (172.7-637.4)

445.9 (198.6-780.4)

356.6 (188.6-693.8)

Regular multivitamin use,d No. (%)

10 (12)

18 (22)

15 (18)

22 (27)

65 (19.8)

Regular vitamin D supplement use,d No. (%)

8 (10)

6 (8)

2 (2)

8 (10)

24 (7.3)

HCTZ use, No. (%)

19

18

12

17

66 (20.1)

Post-menopausal hormone use,e No. (%)

0

0

0

1 (0.5)

1 (0.5)

Regular calcium supplement use,d No. (%)

7 (8.7)

9 (11.1)

7 (8.4)

9(10.8)

32 (9.8)

History of cancer,f No. (%)

6 (7.4)

6 (7.4)

0

3 (3.6)

15 (4.6)

History of hypertension, No. (%)

35 (43.2)

35 (43.2)

36 (43.3)

35 (42.1)

141 (43.0)

  1. aThere were no significant differences in subject characteristics across supplementation arms except where indicated
  2. bMedian; 25th, 75th percentiles in parentheses (all such values) except otherwise stated
  3. cRefers to the intake during the preceding month of selected calcium-rich foods
  4. dDefined as supplement use for 7 days/week during the preceding month
  5. ePercentages were calculated from a total of 222 females
  6. fReported cancers include breast cancer, cervical cancer, uterine cancer, lung cancer, prostate cancer, and sarcoma
  7. gPTH was measured in 254 individuals
  8. Abbreviations: BMI body mass index, PTH parathyroid hormone, 25(OH)D-25 hydroxyvitamin D, HCTZ hydrochlorothiazide)
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