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Table 5 Diet palatability, satiety, and gastrointestinal symptoms experienced on Prudent and Western diets

From: A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study

 

Prudent diet (n = 33 to 45)

Western diet (n = 31 to 45)

Mean difference between Prudent and Western (95 % CI) at 2 weeks

 

Week 0

Week 1

Week 2

Week 0

Week 1

Week 2

 

Palatability, mean (SD) (out of 10)a

8.2 (1.5)

6.9 (1.3)

7.1 (1.4)

7.9 (1.3)

4.6 (1.7)

4.8 (1.4)

2.2 (1.6 to 2.9)

Satiety (-3 to +3)

1.1 (1.1)

1.3 (1.5)

1.2 (1.1)

0.7 (1.3)

1.0 (1.8)

0.9 (1.2)

0.3 (-0.3 to 0.9)b

Gas/bloating, n (%)

 As usual or less than usual

32 (86.5)

26 (76.5)

25 (75.8)

31 (91.2)

22 (62.9)

17 (54.8)

0.047c

 More than usual

5 (13.5)

8 (23.5)

8 (24.2)

3 (8.8)

13 (37.1)

14 (45.2)

# bowel movements per week, mean (SD)

7.6 (5.6)

7.5 (6.2)

7.4 (6.1)

6.8 (4.4)

7.0 (4.2)

6.5 (4.7)

0.4 (-1.5 to 2.2)b

Any days of diarrhea, n (%)

4 (4.9)

4 (4.9)

3 (3.7)

1 (1.2)

3 (3.7)

4 (4.9)

>0.70c

Any days of constipation, n (%)

5 (6.1)

4 (4.9)

1 (1.2)

2 (2.4)

12 (14.6)

9 (11.0)

<0.001c

  1. aWeek 0 is palatability of their usual diet while weeks 1 and 2 reflect the palatability of the intervention diet
  2. bComparison of mean intervention values (week 1 and 2), adjusted for age, sex, and baseline values. Expressed as mean (95 % CI); P < 0.05, P < 0.01, §P < 0.001
  3. cFisher’s exact test for between-treatment differences in distribution of variables during follow up. Counts of number of participants reporting any days of diarrhea, constipation, or more bloating/gas in either week 1 or 2 were collapsed for analysis, if such data were also provided at baseline