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Table 5 Diet palatability, satiety, and gastrointestinal symptoms experienced on Prudent and Western diets

From: A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study

  Prudent diet (n = 33 to 45) Western diet (n = 31 to 45) Mean difference between Prudent and Western (95 % CI) at 2 weeks
  Week 0 Week 1 Week 2 Week 0 Week 1 Week 2  
Palatability, mean (SD) (out of 10)a 8.2 (1.5) 6.9 (1.3) 7.1 (1.4) 7.9 (1.3) 4.6 (1.7) 4.8 (1.4) 2.2 (1.6 to 2.9)
Satiety (-3 to +3) 1.1 (1.1) 1.3 (1.5) 1.2 (1.1) 0.7 (1.3) 1.0 (1.8) 0.9 (1.2) 0.3 (-0.3 to 0.9)b
Gas/bloating, n (%)
 As usual or less than usual 32 (86.5) 26 (76.5) 25 (75.8) 31 (91.2) 22 (62.9) 17 (54.8) 0.047c
 More than usual 5 (13.5) 8 (23.5) 8 (24.2) 3 (8.8) 13 (37.1) 14 (45.2)
# bowel movements per week, mean (SD) 7.6 (5.6) 7.5 (6.2) 7.4 (6.1) 6.8 (4.4) 7.0 (4.2) 6.5 (4.7) 0.4 (-1.5 to 2.2)b
Any days of diarrhea, n (%) 4 (4.9) 4 (4.9) 3 (3.7) 1 (1.2) 3 (3.7) 4 (4.9) >0.70c
Any days of constipation, n (%) 5 (6.1) 4 (4.9) 1 (1.2) 2 (2.4) 12 (14.6) 9 (11.0) <0.001c
  1. aWeek 0 is palatability of their usual diet while weeks 1 and 2 reflect the palatability of the intervention diet
  2. bComparison of mean intervention values (week 1 and 2), adjusted for age, sex, and baseline values. Expressed as mean (95 % CI); P < 0.05, P < 0.01, §P < 0.001
  3. cFisher’s exact test for between-treatment differences in distribution of variables during follow up. Counts of number of participants reporting any days of diarrhea, constipation, or more bloating/gas in either week 1 or 2 were collapsed for analysis, if such data were also provided at baseline