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Table 2 Associations between nutrient intake and LDL-C concentration according to three dietary assessment methods

From: Relationship between ethanol consumption and TBL2 rs17145738 on LDL-C concentration in Japanese adults: a four season 3-day weighed diet record study

 

Complete case dataseta

Observed subject datasetb

Multiple imputation dataset (m = 100)c

 

β

SE

P

β

SE

P

β

SE

P

Cross-sectional study

 FFQ (one year)d

  Number of observations (person · season)

 

51

  

73

  

78

 

  Fat (g/MJ)

7.9 × E-3

1.1 × E-2

0.48

9.9 × E-3

9.9 × E-3

0.32

1.1 × E-2

9.7 × E-3

0.27

  Cholesterol (mg/MJ)

2.3 × E-2

1.6 × E-1

0.89

1.3 × E-2

1.3 × E-1

0.92

2.9 × E-2

1.3 × E-1

0.82

  TDF (g/MJ)

-3.2 × E-2

1.9 × E-1

0.87

1.3 × E-2

1.5 × E-1

0.93

3.1 × E-2

1.5 × E-1

0.84

  Ethanol (g/day)

-7.3 × E-2

2.6 × E-2

0.008

-3.8 × E-2

2.1 × E-2

0.07

-3.6 × E-2

2.1 × E-2

0.09

 First season, 3-day WDRd

  Number of observations (person · season)

 

51

  

72

  

78

 

  Fat (g/MJ)

3.4 × E-4

1.2 × E-2

0.98

-6.3 × E-3

8.9 × E-3

0.48

-6.9 × E-3

8.6 × E-3

0.42

  Cholesterol (mg/MJ)

6.0 × E-2

1.3 × E-1

0.64

-1.2 × E-2

9.1 × E-2

0.89

-9.0 × E-3

8.7 × E-2

0.92

  TDF (g/MJ)

-2.9 × E-1

1.2 × E-1

0.02

-1.2 × E-1

9.0 × E-2

0.20

-1.0 × E-1

8.9 × E-2

0.26

  Ethanol (g/day)

-7.9 × E-2

3.1 × E-2

0.02

-6.3 × E-2

2.4 × E-2

0.01

-5.8 × E-2

2.4 × E-2

0.02

Seasonal variation research

 Four season, 3-day WDRe

  Number of observations (person · season)

 

204

  

262

  

312

 

  Fat (g/MJ)

-5.3 × E-4

3.8 × E-3

0.89

-1.0 × E-3

3.2 × E-3

0.76

-1.0 × E-3

4.2 × E-3

0.81

Season - Winter

Reference

Reference

Reference

   - Spring

-1.4 × E-2

9.2 × E-3

0.13

-1.6 × E-2

7.9 × E-3

0.04

-1.6 × E-2

1.1 × E-2

0.14

   - Summer

-2.8 × E-2

9.1 × E-3

0.003

-2.5 × E-2

7.8 × E-3

0.002

-2.2 × E-2

1.0 × E-2

0.04

   - Autumn

-1.4 × E-2

9.1 × E-3

0.13

-1.5 × E-2

8.2 × E-3

0.08

-1.1 × E-2

1.1 × E-2

0.34

  Cholesterol (mg/MJ)

7.2 × E-2

3.1 × E-2

0.02

5.3 × E-2

2.6 × E-2

0.04

5.0 × E-2

3.8 × E-2

0.19

Season - Winter

Reference

Reference

Reference

   - Spring

-1.7 × E-2

9.0 × E-3

0.06

-1.8 × E-2

7.7 × E-3

0.02

-1.8 × E-2

1.0 × E-2

0.09

   - Summer

-3.0 × E-2

9.0 × E-3

0.001

-2.7 × E-2

7.8 × E-3

<0.001

-2.4 × E-2

1.0 × E-2

0.02

   - Autumn

-1.8 × E-2

9.0 × E-3

0.05

-1.7 × E-2

8.2 × E-3

0.04

-1.3 × E-2

1.1 × E-2

0.24

  TDF (g/MJ)

-7.1 × E-3

3.3 × E-2

0.83

-2.2 × E-2

2.9 × E-2

0.46

-2.7 × E-2

4.3 × E-2

0.52

Season - Winter

Reference

Reference

Reference

   - Spring

-1.4 × E-2

9.1 × E-3

0.12

-1.7 × E-2

7.8 × E-3

0.03

-1.6 × E-2

1.1 × E-2

0.12

   - Summer

-2.8 × E-2

9.2 × E-3

0.003

-2.5 × E-2

7.9 × E-3

0.002

-2.3 × E-2

1.1 × E-2

0.03

   - Autumn

-1.4 × E-2

9.0 × E-3

0.12

-1.5 × E-2

8.2 × E-3

0.07

-1.1 × E-2

1.1 × E-2

0.34

  Ethanol (g/day)

-2.1 × E-2

1.3 × E-2

0.12

-1.9 × E-2

1.0 × E-2

0.07

-2.7 × E-2

1.5 × E-2

0.08

Season - winter

Reference

Reference

Reference

   - Spring

-1.5 × E-2

8.9 × E-3

0.11

-1.7 × E-2

7.8 × E-3

0.03

-1.6 × E-2

1.1 × E-2

0.13

   - Summer

-2.8 × E-2

8.9 × E-3

0.002

-2.4 × E-2

7.7 × E-3

0.002

-2.2 × E-2

1.1 × E-2

0.04

   - Autumn

-1.4 × E-2

9.0 × E-3

0.12

-1.5 × E-2

8.2 × E-3

0.07

-1.1 × E-2

1.1 × E-2

0.34

  1. Abbreviations: LDL-C LDL cholesterol, FFQ food frequency questionnaire, 3-day WDR 3-day weighed dietary records, TDF total dietary fiber, m number of imputations. The following variables were log-transformed to improve the normality: LDL-C concentration; dietary cholesterol; TDF; BMI; physical activity; ethanol consumption. P <0.05 was shown as bold. aComplete case dataset was composed of subjects without missing values on four seasons. bObserved subjects dataset was used for the analysis of all of values collected in each season even if there were missing values. cMultiple imputation datasets were calculated by means of applying observed subjects dataset to the MI procedure. dMultiple regression models were applied for analyzing the associations between nutrient intake and LDL-C concentration with adjustment for age, sex (0, men; 1, women), BMI, physical activity, ethanol consumption, smoking status (0, non-smoker; 1, smoker) and energy intake. eMixed-effect models were applied for analyzing the associations between nutrient intake and LDL-C concentration with fixed effect: season (1, winter; 2, spring; 3 summer; 4, autumn), age, sex (0, men; 1, women), BMI, physical activity, ethanol consumption, smoking status (0, non-smoker; 1, smoker) and energy intake and random intercept: subject ID