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Table 3 Changes in biochemical parameters and blood pressure of individuals

From: Time-restricted eating (16/8) and energy-restricted diet: effects on diet quality, body composition and biochemical parameters in healthy overweight females

Variables

TRE group (n = 10)

ERD group (n = 13)

Statistical analysis between differencea

At the beginning

At the end

Difference

p-value

At the beginning

At the end

Difference

p-value

Fasting glucose (mg/dL)

89.00 (13.75)

91.50 (19.25)

-1.9 ± 8.08 (%2.1 ± 9.45)

0.386

91.00 (5.50)

85.00 (9.50)

-3.7 ± 6.22 (%3.9 ± 7.19)

0.054

0.663

Insulin (µIU/mL)

6.45 (4.28)

5.60 (6.10)

-0.2 ± 4.08 (%10.6 ± 6.74)

0.838

8.20 (7.10)

6.70 (8.65)

-1.3 ± 6.03 (%4.5 ± 71.4)

0.249

0.402

HOMA-IR

1.37 (1.22)

1.28 (1.34)

-0.1 ± 0.93 (%9.8 ± 63.73)

0.959

1.68 (1.70)

1.31 (1.73)

-0.3 ± 1.35 (%7.5 ± 72.9)

0.173

0.385

Total cholesterol (mg/dL)

186.50 (17.00)

178.00 (13.75)

-13.9 ± 12.82 (%6.7 ± 5.89)

0.008*

191.00 (54.00)

179.00 (49.00)

-6.8 ± 11.11 (%3.7 ± 6.7)

0.043*

0.145

LDL-C (mg/dL)

116.50 (17.50)

107.00 (16.25)

-9.1 ± 11.25 (%6.5 ± 9.91)

0.008*

126.00 (44.00)

117.00 (53.50)

-4.5 ± 10.75 (%3.7 ± 10.1)

0.239

0.251

HDL-C (mg/dL)

54.00 (21.00)

52.00 (11.50)

-7.7 ± 10.61 (%10.8 ± 15.35)

0.074

50.00 (15.00)

44.00 (12.00)

-3.3 ± 5.29 (%5.2 ± 10.2)

0.058

0.437

Triglyceride (mg/dL)

89.00 (40.50)

108.50 (32.75)

15.4 ± 27.41 (%24.1 ± 34.89)

0.114

82.00 (52.00)

94.00 (41.50)

4.1 ± 39.67 (%7.9 ± 39.4)

0.944

0.128

 C-Reactive Protein (mg/L)

3.98 (4.18)

3.09 (3.26)

-0.8 ± 1.97 (1.8 ± 65.85)

0.241

1.96 (3.26)

1.94 (2.55)

-0.6 ± 2.85 (%4.0 ± 38.2)

1.000

0.264

IL-6 (pg/mL)

2.07 (1.82)

1.50 (0.97)

1.7 ± 7.11 (%72.0 ± 235.1)

0.866

1.97 (2.92)

2.22 (2.44)

-0.2 ± 5.57 (%66.7 ± 232.9)

0.374

0.801

Total Antioxidant Status (mmol/L)

1.19 (0.23)

1.30 (0.59)

0.04 ± 0.38 (%5.4 ± 31.58)

0.646

1.27 (0.29)

1.46 (0.36)

0.2 ± 0.20 (%13.2 ± 17.9)

0.023*

0.368

Total Oxidant Status (µmol/L)

4.38 (1.56)

5.16 (1.51)

0.23 ± 1.26 (%8.9 ± 29.27)

0.594

4.51 (1.89)

5.42 (2.92)

1.2 ± 2.36 (%33.1 ± 54.9)

0.173

0.264

Oxidative Stress Index

0.39 (0.12)

0.41 (0.11)

0.02 ± 0.09 (%7.1 ± 24.93)

0.415

0.36 (0.17)

0.44 (0.12)

0.03 ± 0.14 (%17.0 ± 43.3)

0.382

0.664

Leptin (pg/mL)

13600.26 (13338.46)

7400.58 (6655.05)

-3226.8 ± 7657.80 (%1.3 ± 78.46)

0.333

6676.70 (7111.13)

7206.72 (8755.19)

306.2 ± 4628.46 (%2.8 ± 35.8)

0.650

0.336

Adiponectin (ng/mL)

9377.15 (4054.99)

11058.93 (3393.05)

508.8 ± 2649.30 (%11.2 ± 39.82)

0.878

5482.65 (3063.65)

9393.08 (5105.05)

3189.3 ± 2760.60 (%77.3 ± 58.9)

0.006*

0.035*

Systolic Blood Pressure (mmHg)

105.00 (5.25)

108.00 (16.00)

1.6 ± 8.01 (%1.9 ± 7.91)

0.609

104.00 (22.00)

91.00 (16.00)

-3.7 ± 10.76 (%2.7 ± 11.6)

0.248

0.162

Diastolic Blood Pressure (mmHg)

70.00 (16.75)

72.50 (15.75)

1.2 ± 11.05 (%2.7 ± 16.05)

1.000

63.00 (20.50)

63.00 (11.00)

-1.4 ± 8.58 (%0.7 ± 14.1)

p = 0.529

0.686

Heart rate (bpm)

79.00 (9.00)

78.00 (15.75)

-2.0 ± 8.65 (%2.5 ± 11.12)

0.540

71.00 (19.00)

76.00 (19.50)

-0.7 ± 7.10 (%1.0 ± 10.5)

p = 0.893

0.514

  1. Median with interquartile range, a Mann-Withney U test, other tests Wilcoxon test, *p < 0.05
  2. HOMA-IR: Homeostatic Model Assessment of Insulin Resistance, LDL-C: Low density lipoprotein cholesterol, HDL-C: High density lipoprotein cholesterol, IL-6: Interleukin 6