Table 1 Baseline demographics of the mother–child pairs
Characteristic | All | B12 group | Placebo | p-value |
|---|---|---|---|---|
Pregnant women | ||||
Age of women (years) | 22.5 ± 3.6 | 22.6 ± 3.34 | 22.3 ± 3.86 | 0.691 |
BMI at GW8 (kg/m2) | 21.2 ± 4 | 21.6 ± 1.91 | 22.1 ± 1.74 | 0.221 |
Delivery mode | ||||
Vaginal | 54 (74.0%) | 24(68.6%) | 30(78.9%) | 0.229 |
Cesarian | 19 (26.0%) | 11(31.4%) | 8(21.1%) | |
Gestational age, GW (weeks) | 38.8 ± 1.8 | 38.2 ± 1.90 | 38.6 ± 1.62 | 0.388 |
Hb (g/dL) | 11.2 ± 0.92 | 11.2 ± 0.86 | 11.2 ± 1.00 | 0.867 |
Folate, nmol/L | 8.3 ± 4.1 | 8.99 ± 4.81 | 7.74 ± 3.45 | 0.213 |
B12, pg/mL | 139.2 (109.7, 176.43) | 142.3(109.1, 163.8) | 134.7(110.5, 201.7) | 0.714 |
tHcy, µmol/L | 9.2 (8.0, 11.0) | 9.30(8.20, 11.5) | 9.00(7.90, 10.5) | 0.314 |
MMA, nmol/L | 220.0 (168.0, 324.0) | 228.0(158.0, 317.0) | 219.5(148.0, 318.5) | |
Children | ||||
Birth weight (g) | 2,786 ± 385 | 2,776 ± 338 | 2,796 ± 410 | 0.811 |
Boys | 37 (50.7%) | 18(51.4%) | 19(50.0%) | 0.545 |
Girls | 36 (49.3%) | 17(48.6%) | 19(50.0%) | |