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Table 1 Characteristics of included studies

From: The effects of Mediterranean diet on cardiovascular risk factors, glycemic control and weight loss in patients with type 2 diabetes: a meta-analysis

First author

Year

Country

Participants

No.of cases

Age

During design

Mediterranean diet intervention

Control intervention

Available outcomes

Brehm [30]

2009

United states

Overweight/obese adults with well-controlled T2D

124 (95 completers)

38-75

1 year

High intake of olive, nuts, seeds, legumes;45% carbohydrate, 15% protein and 40% fat(with 20% MUFA, emphasizing olive and canola oils)

High-carbohydrate diet:60% carbohydrate,15% protein and 25% fat

HbA1c,fasting plasma glucose, fasting insulin, HOMA-IR, body weight, TC, LDL, HDL and blood pressure

Toobert [31]

2003

United states

Post-menopausal women with T2D

279 (245 completers)

<75

6 month

The diet recommended increased amounts of bread, root vegetables, green vegetables, legumes, and fish; less red meat (e.g, beef, lamb, and pork), substituting poultry; no day without fruit; and avoidance of butter and cream, substituting olive oil/canolaoil or commercially available olive oil/can

Usual care(no information provided)

HbA1c,triglyceride s,TC, HDL, LDL, BMI, SBP, DBP

Elhayany [17]

2010

Israel

Overweight adults with T2D

259 (179 completers)

30-65

1 year

A low-carbohydrate mediterranean diet (50-55% LGI carbohydrate, 45% fat-high in MUFA and 20% protein)

A traditional mediterranean diet (50-55% LGI carbohydrate, 30% fat-high in MUFA and 15-20% protein)

American Diabetes

Association diet: 50-55% carbohydrate of a mixed glycemic index,30% fat and 15-20% protein.

Weight, BMI, waist circumference, fasting plasma glucose, HbA1c, trig lycerides, TC, HDL, LDL,, fasting insulin,HOMA-IR

Maiorino [32]

2016

Italy

Adults with newly

Diagnosed T2D

215 (201 completers)

Mean 52

8.1years

Rich in whole grains and vegetables,low in red meat, >30% calories from fat,30 to 50g of olive oil, <50% calories from carbohydrate

Low-fat diet:<30% calories from fat(<10% calories from saturated fat),with restricted additional fats,sweets and high-fat snacks

Weight,WC,HbA1c, plasma glucose,triglycerides, TC , HDL , LDL, SBP,DBP

Maryam [19]

2020

Iran

Adults with T2D

228

40-60

6 month

Received 8 education sections and underwent classic MD in 25-person groups in two times by nutritionist.

Usual care(no information provided)

Fasting blood glucose,HbA1c,trig lycerides, TC , HDL, LDL, SBP, DBP, BMI

Alonso-Dominguez [33]

2019

Spain

Adults with T2D

204 (185 completers)

25-70

Mean 60.6

1 year

Received brief advice about healthy eating and physical activity, and took part in a food workshop, five walks and received a smartphone application for three months

Usual care(no information provided)

Glycated haemoglobin,Postp randial glucose,Atherogeni c index, TC, HDL, LDL, Waist circumference, SBP, DBP

Toobert [34]

2011

United States

Latinas with T2D

280

Mean 57

2 year

Emphasis on vegetables, legumes,cereals, cereals, fruits, nuts, olive oil and limited fat

Usual care (no information provided)

HbA1c, BMI