Hypolipidemic effect and activation of Lecithin Cholesterol Acyl Transferase (LCAT) by aqueous extract of Spirulina platensis during toxicological investigation

Table 3 Biochemical parameters of females and males rats after 28 days administration of Spirulina platensis

	DOSES mg/kg bw	Alb (g/l)	Urea (g/l)	Creatinine (mg/l)	AST (UI/l)	ALT (UI/l)	T Bili (mg/l)	D Bili mg/l
Females	Control	34.75 ± 1.29	0.59 ± 0.06	9.94 ± 1.33	295.93 ± 32.85	64.11 ± 7.23	1.23 ± 0.48	0.43 ± 0.31
	250	35.65 ± 1.41	0.53 ± 0.05	9.04 ± 0.57	324.05 ± 78.35	71.71 ± 20.47	1.34 ± 0.36	0.39 ± 0.19
	500	33.9 33.98 ± 2.63	0.62 ± 0.12	8.65 ± 1.59	288.70 ± 58.60	68.54 ± 23.08	0.95 ± 0.22	0.32 ± 0.14
	1000	35.01 ± 0.75	0.53 ± 0.10	9.96 ± 1.08	379.43 ± 126.9	77.17 ± 19.96	1.48 ± 0.26	0.55 ± 0.07
Males	Control	34.23 ± 0.94^a	0.62 ± 0.24	8.97 ± 1.75	344.75 ± 136.46	91.58 ± 37.29	1.07 ± 0.20	0.42 ± 0.19
	250	36.31 ± 0.82^ab	0.56 ± 0.21	9.30 ± 0.76	337.78 ± 125.44	80.32 ± 18.59	1.26 ± 0.38	0.52 ± 0.42
	500	31.07 ± 2.42^c	0.62 ± 0.14	9.24 ± 0.67	291.90 ± 22.72	112.39 ± 33.07	1.14 ± 0.41	0.51 ± 0.19
	1000	34.58 ± 0.62^a	0.61 ± 0.07	9.02 ± 0.33	357.86 ± 75.02	102.29 ± 16.56	1.25 ± 0.26	0.46 ± 0.15

In the same column, the values subscripted with the same letter are not significantly different at p < 0.05
Bw body weight, AST Aspartate Amino transferase, ALT Alanine Amino Transferase, T Bili total bilirubin, D Bili direct bilirubin, Alb albumin

ISSN: 2055-0928