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Table 3 Biochemical parameters of females and males rats after 28 days administration of Spirulina platensis

From: Hypolipidemic effect and activation of Lecithin Cholesterol Acyl Transferase (LCAT) by aqueous extract of Spirulina platensis during toxicological investigation

  DOSES
mg/kg bw
Alb
(g/l)
Urea
(g/l)
Creatinine
(mg/l)
AST
(UI/l)
ALT
(UI/l)
T Bili
(mg/l)
D Bili
mg/l
Females Control 34.75 ± 1.29 0.59 ± 0.06 9.94 ± 1.33 295.93 ± 32.85 64.11 ± 7.23 1.23 ± 0.48 0.43 ± 0.31
250 35.65 ± 1.41 0.53 ± 0.05 9.04 ± 0.57 324.05 ± 78.35 71.71 ± 20.47 1.34 ± 0.36 0.39 ± 0.19
500 33.9 33.98 ± 2.63 0.62 ± 0.12 8.65 ± 1.59 288.70 ± 58.60 68.54 ± 23.08 0.95 ± 0.22 0.32 ± 0.14
1000 35.01 ± 0.75 0.53 ± 0.10 9.96 ± 1.08 379.43 ± 126.9 77.17 ± 19.96 1.48 ± 0.26 0.55 ± 0.07
Males Control 34.23 ± 0.94a 0.62 ± 0.24 8.97 ± 1.75 344.75 ± 136.46 91.58 ± 37.29 1.07 ± 0.20 0.42 ± 0.19
250 36.31 ± 0.82ab 0.56 ± 0.21 9.30 ± 0.76 337.78 ± 125.44 80.32 ± 18.59 1.26 ± 0.38 0.52 ± 0.42
500 31.07 ± 2.42c 0.62 ± 0.14 9.24 ± 0.67 291.90 ± 22.72 112.39 ± 33.07 1.14 ± 0.41 0.51 ± 0.19
1000 34.58 ± 0.62a 0.61 ± 0.07 9.02 ± 0.33 357.86 ± 75.02 102.29 ± 16.56 1.25 ± 0.26 0.46 ± 0.15
  1. In the same column, the values subscripted with the same letter are not significantly different at p < 0.05
  2. Bw body weight, AST Aspartate Amino transferase, ALT Alanine Amino Transferase, T Bili total bilirubin, D Bili direct bilirubin, Alb albumin
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