Table 3 Fasting blood lipid concentrations based on SNPs in the examined genes
Gene & genotype (n) | TG (mg/dL) | Total cholesterol (mg/dL) | HDL-C (mg/dL) | LDL-C (mg/dL) | NEFA (mEq/L) |
|---|---|---|---|---|---|
APOA5 | |||||
 CC (1) + CG (46) | 90.69 ± 5.20 | 179.3 ± 4.67 | 52.04 ± 1.88 | 116.7 ± 4.23 | 0.31 ± 0.02 |
 GG (302) | 87.72 ± 1.92 | 174.2 ± 1.81 | 55.78 ± 0.96 | 108.7 ± 1.64 | 0.32 ± 0.01 |
 % change of the C allele | 3.27 | 2.84 | -7.19 | 6.86 | -3.23 |
APOB | |||||
 GG (27) + AG (127) | 88.57 ± 2.80 | 174.7 ± 2.57 | 56.43 ± 1.10 | 108.9 ± 2.33 | 0.32 ± 0.01 |
 AA (192) | 87.74 ± 2.48 | 175.0 ± 2.30 | 54.39 ± 0.98 | 110.4 ± 2.08 | 0.32 ± 0.01 |
 % change of the G allele | 0.95 | -0.17 | 3.62 | -1.38 | 0 |
APOC3 | |||||
 CC (63) + CT (167) | 87.74 ± 2.25 | 177.5 ± 2.07 | 55.95 ± 0.90 | 111.8 ± 1.89 | 0.33 ± 0.01 |
 TT (117) | 88.30 ± 3.19 | 169.5 ± 2.93 | 54.01 ± 1.27 | 105.7 ± 2.67 | 0.30 ± 0.01 |
 % change of the C allele | -0.64 | 4.51 * | 3.47 | 5.46 | 9.09 |
APOE | |||||
 CC (4) + CT (92) | 93.08 ± 3.74 | 179.1 ± 3.28 | 52.62 ± 1.41 | 116.2 ± 2.96 | 0.33 ± 0.01 |
 TT (253) | 86.30 ± 2.11 | 173.2 ± 1.99 | 56.29 ± 0.85 | 107.4 ± 1.80 | 0.31 ± 0.01 |
 % change of the C allele | 7.28 | 3.29 | -6.97 * | 7.57 * | 6.06 |
LDLR | |||||
 CT (59) + TT (3) | 88.98 ± 4.43 | 178.8 ± 4.05 | 57.73 ± 1.74 | 110.8 ± 3.69 | 0.32 ± 0.02 |
 CC (286) | 87.94 ± 2.02 | 174.0 ± 1.87 | 54.74 ± 0.80 | 109.5 ± 1.70 | 0.32 ± 0.01 |
 % change of the T allele | 1.17 | 2.68 | 5.18 | 1.18 | 0 |