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Table 4 Expression level of miRNAs in BT-474 cell line

From: Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells

BT-474

Normoxic

Hypoxic

Treated with DHA

Treated with CoCl2

Treated with DHA and CoCl2

 

Fold change

P-value*

Fold change

P-value**

Fold change

P-value***

MiR-142

5.268704

< 0.0001

-3.6217

< 0.0001

5.263158

< 0.0001

MiR-30a

769.2308

< 0.0001

238.0952

0.0001

1.923077

0.0004

MiR-133a

1.85701

< 0.0001

-7092.19

< 0.0001

3448.276

< 0.0001

MiR-194

952.381

< 0.0001

292.8258

< 0.0001

1.785714

< 0.0001

MiR-424

4.496403

< 0.0001

-3.0065

0.0007

4

0.0001

MiR-155

2500

< 0.0001

432.9004

0.0026

3.571429

< 0.0001

MiR-143

2941.176

< 0.0001

2.765487

> 0.9999

113.6364

0.0004

  1. *: compared control with DHA treated group
  2. **: compared control with CoCl2 treated group
  3. ***: compared CoCl2 treated group with DHA + CoCl2 treated group