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Table 5 Expression level of miRNAs in MDA-MB-231 cell line

From: Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells

MDA-MB-231

Normoxic

Hypoxic

Treated with DHA

Treated with CoCl2

Treated with DHA and CoCl2

 

Fold change

P-value*

Fold change

P-value**

Fold change

P-value***

MiR-142

4.657662

< 0.0001

-24.720

< 0.0001

25.64103

< 0.0001

MiR-30a

2.254283

< 0.0001

-3.3951

0.0006

2.040816

0.0999

MiR-133a

2.524615

0.0002

-128.2544

0.0030

50

0.3133

MiR-194

-1.4239

0.0005

-2.666

< 0.0001

1.408451

0.0465

MiR-424

2.615063

< 0.0001

1.230769

0.4314

NS

1.694915

0.0047

MiR-155

17.33102

< 0.0001

-1.9293

0.0153

3.703704

< 0.0001

MiR-143

8.547009

< 0.0001

3.575259

0.0002

1.612903

0.0011

  1. *: compared control with DHA treated group
  2. **: compared control with CoCl2 treated group
  3. ***: compared CoCl2 treated group with DHA + CoCl2 treated group
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BMC Nutrition

ISSN: 2055-0928

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