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Table 8 Expression level of miRNAs in exosomes-derived BT-474 cell line

From: Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells

Exo-BT-474

Normoxic

Hypoxic

Treated with DHA

Treated with CoCl2

Treated with DHA and CoCl2

 

Fold change

P-value*

Fold change

P-value**

Fold change

P-value***

MiR-142

-71.46

< 0.0001

-3154.57

< 0.0001

12.34568

0.4330

MiR-30a

6.60502

< 0.0001

3.386387

< 0.0001

-27.64

< 0.0001

MiR-133a

-2444.98

< 0.0001

-4032.25

< 0.0001

1.315789

0.0392

MiR-194

-3.5385

< 0.0001

-4.4471

< 0.0001

2.631579

< 0.0001

MiR-424

-1785.71

< 0.0001

-315457.4

< 0.0001

29.41176

0.0115

MiR-155

-4.996

0.0002

-442.67

< 0.0001

90.90909

0.3112

MiR-143

131.2336

< 0.0001

-18.3297

0.8760

434.7826

< 0.0001

  1. *: compared control with DHA treated group
  2. **: compared control with CoCl2 treated group
  3. ***: compared CoCl2 treated group with DHA + CoCl2 treated group
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BMC Nutrition

ISSN: 2055-0928

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