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Table 9 Expression level of miRNAs in exosomes-derived MDA-MB-231 cell line

From: Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells

Exo-MDA-MB-231

Normoxic

Hypoxic

Treated with DHA

Treated with CoCl2

Treated with DHA and CoCl2

 

Fold change

P-value*

Fold change

P-value**

Fold change

P-value***

MiR-142

26.02811

< 0.0001

3.238342

0.0002

3.225806

< 0.0001

MiR-30a

15.38462

< 0.0001

-1.8946

0.0071

3.333333

< 0.0001

MiR-133a

13.07702

< 0.0001

1.01688

0.9806

3.030303

< 0.0001

MiR-194

3030.303

< 0.0001

1785.714

< 0.0001

1.030928

0.9508

MiR-424

16.42036

< 0.0001

-6.9105

0.0659

62.5

< 0.0001

MiR-155

502.5126

< 0.0001

281.6901

< 0.0001

1.298701

< 0.0001

MiR-143

5263.158

< 0.0001

219.7802

< 0.0001

4.545455

< 0.0001

  1. *: compared control with DHA treated group
  2. **: compared control with CoCl2 treated group
  3. ***: compared CoCl2 treated group with DHA + CoCl2 treated group
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BMC Nutrition

ISSN: 2055-0928

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